Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.56 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.37 |
| ▸ | TUBB | P07437 | 1/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8073542 | 0.88 | PKM (0.59) | PKMLMNASMN1; SMN2MCL1HTT | |
| SCHEMBL18138448 | 0.83 | PKM (0.56) | PKMLMNASMN1; SMN2MCL1HTT | |
| SCHEMBL4222267 | 0.81 | PKM (0.55) | PKMLMNASMN1; SMN2MCL1HTT | |
| SCHEMBL13778225 | 0.81 | PKM (0.55) | PKMLMNASMN1; SMN2MCL1HTT | |
| SCHEMBL9820284 | 0.81 | TDP1 (0.41) | PKMCHEK1SMN1; SMN2HTTALDH1A1 | |
| Bromide SCHEMBL4217783 | 0.80 | PKM (0.54) | PKMLMNASMN1; SMN2MCL1HTT | |
| SCHEMBL9681717 | 0.79 | PKM (0.52) | PKMLMNASMN1; SMN2MCL1HTT | |
| SCHEMBL9348700 | 0.77 | PKM (0.65) | PKMLMNASMN1; SMN2MCL1HTT | |
| SCHEMBL6573968 | 0.76 | RAB9A (0.55) | CHEK1LMNASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL2905398 | 0.76 | PKM (0.59) | PKMLMNASMN1; SMN2MCL1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7560491-B2 | Z-stilbenes derivatives and the pharmaceutical composition thereof | TAIPEI MEDICAL UNIVERSITY (TW) | 2009-07-14 | — | — | US | disclosed |
| US-20080096973-A1 | Z-stilbenes derivatives and the pharmaceutical composition thereof | TAIPEI MEDICAL UNIVERSITY (TW) | 2008-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080096973-A1 | Z-stilbenes derivatives and the pharmaceutical composition thereof | CCNB1, ZYX, H1-0 | PKM 2125/4885CHEK1 482/4885LMNA 1710/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.