Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A known ✓ | P37288 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.55 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.53 |
| ▸ | F7 | P08709 | 1/20 | 0.50 |
| ▸ | F3 | P13726 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | SPR | P35270 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL154688 | 0.89 | GPR84 (0.63) | NR4A2GPR84F7F3ALDH1A1 | |
| Butyric Acid SCHEMBL432996 | 0.86 | GPR84 (0.50) | NR4A2GPR84F7F3ALDH1A1 | |
| Sulfuric Acid SCHEMBL22441041 | 0.85 | GPR84 (0.54) | NR4A2GPR84F7F3ALDH1A1 | |
| Phosphoric Acid SCHEMBL431773 | 0.85 | GPR84 (0.54) | NR4A2GPR84F7F3ALDH1A1 | |
| Octanoic Acid SCHEMBL2155766 | 0.81 | GSK3B (0.47) | NR4A2GPR84ALDH1A1MEN1KMT2A | |
| Palmitic Acid SCHEMBL432580 | 0.81 | GSK3B (0.47) | NR4A2GPR84ALDH1A1MEN1KMT2A | |
| Nonanoate SCHEMBL27828760 | 0.81 | GSK3B (0.47) | NR4A2GPR84ALDH1A1MEN1KMT2A | |
| Acetic Acid SCHEMBL25368692 | 0.80 | CYP2A6 (0.50) | NR4A2MTNR1AMTNR1B | |
| SCHEMBL3182218 | 0.78 | NR4A2 (0.69) | NR4A2GPR84F7F3ALDH1A1 | |
| SCHEMBL24815224 | 0.78 | GPR84 (0.63) | NR4A2GPR84F7F3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8420345-B2 | Method for identifying at least two groups of microorganisms | BIOMERIEUX (FR) | 2013-04-16 | — | — | US | disclosed |
| US-20090017481-A1 | Method For Identifying at Least Two Groups of Microorganisms | BIOMERIEUX (FR) | 2009-01-15 | — | — | US | disclosed |
| US-7141387-B2 | Microorganism culture medium | CHISSO CORPORATION (JP) | 2006-11-28 | — | — | US | disclosed |
| US-20060008867-A1 | Microorganism culture medium | CHISSO CORPORATION (JP) | 2006-01-12 | — | — | US | disclosed |