Phosphoric Acid

Phosphoric Acid

SCHEMBL431773

O=P(O)(O)O.Oc1c[nH]c2cc(Cl)ccc12

nearest known ligand 0.54

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 2/20 0.54
NR4A2 P43354 2/20 0.49
ALDH1A1 P00352 1/20 0.47
F7 P08709 1/20 0.44
F3 P13726 1/20 0.44
SLC6A4 P31645 1/20 0.43
IDO1 P14902 1/20 0.41
DAO P14920 2/20 0.41
GUSB P08236 1/20 0.40
DYRK1A Q13627 1/20 0.39
SPR P35270 1/20 0.39
GRIN2D O15399 1/20 0.39
GRIN3B O60391 1/20 0.39
GRIN1 Q05586 1/20 0.39
GRIN2A Q12879 1/20 0.39
GRIN2B Q13224 1/20 0.39
GRIN2C Q14957 1/20 0.39
GRIN3A Q8TCU5 1/20 0.39
PARP1 P09874 1/20 0.39
PTGS1 P23219 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL154688 0.91 GPR84 (0.63) GPR84NR4A2ALDH1A1F7F3
Phosphoric Acid SCHEMBL27944654 0.86 F7 (0.56) GPR84NR4A2F7F3
Sulfuric Acid SCHEMBL22441041 0.86 GPR84 (0.54) GPR84NR4A2ALDH1A1F7F3
Acetic Acid SCHEMBL4223403 0.85 NR4A2 (0.55) GPR84NR4A2ALDH1A1F7F3
Choline SCHEMBL7047847 0.80 GPR84 (0.43) GPR84NR4A2ALDH1A1F7F3
SCHEMBL28780337 0.79 GPR84 (0.50) GPR84NR4A2ALDH1A1F7F3
Phosphoric Acid SCHEMBL20573143 0.79 CYP2A6 (0.51) GPR84NR4A2IDO1GUSB
Phosphoric Acid SCHEMBL1231445 0.79 GPR84 (0.54) GPR84IDO1
Butyric Acid SCHEMBL432996 0.79 GPR84 (0.50) GPR84NR4A2ALDH1A1F7F3
SCHEMBL17439076 0.76 F7 (0.59) GPR84NR4A2F7F3SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200298233-A1 MICROFLUIDIC PAPER CHIP FOR DETECTING MICRO-ORGANISM, METHOD FOR PREPARING THE SAME AND METHOD FOR DETECTING MICRO-ORGANISM USING THE SAME BIOMAX CO., LTD. (KR) 2020-09-24 US claimed
EP-2972345-B1 A FLOW-THROUGH CELL COUNTING ASSAY ALLIED INNOVATIVE SYSTEMS LLC (US) 2018-01-17 EP claimed
US-20170167956-A1 SEALING FLUID FOR MICROFLUIDIC ANALYSES DIAGNOSTIC BIOSYSTEMS (US) 2017-06-15 US claimed
EP-2972345-A1 A FLOW-THROUGH CELL COUNTING ASSAY Allied Innovative Systems, LLC (US) 2016-01-20 EP claimed
US-9097712-B2 Flow-through cell counting assay ALLIED INNOVATIVE SYSTEMS LLC (US) 2015-08-04 US claimed
WO-2014149310-A1 A FLOW-THROUGH CELL COUNTING ASSAY ALLIED INNOVATIVE SYSTEMS, LLC (US) 2014-09-25 WO claimed
US-20140273018-A1 FLOW-THROUGH CELL COUNTING ASSAY ALLIED INNOVATIVE SYSTEMS, LLC (US) 2014-09-18 US claimed
US-20100243479-A1 SENSOR FOR DETECTING STEM CELL DIFFERENTIATION BASED ON ELECTROCHEMICAL METHODS Industry-University Cooperation Foundation Sogang University (KR) 2010-09-30 US claimed
US-6902586-B2 Phosphate dye precursors and use thereof for dyeing keratin fibers L'OREAL (FR) 2005-06-07 US claimed
EP-1273283-B1 Phosphated dye precursors and their application for dyeing keratinous fibres OREAL (FR) 2004-10-06 EP claimed
US-20030037387-A1 Phosphate dye precursors and use thereof for dyeing keratin fibres L'OREAL (FR) 2003-02-27 US claimed
EP-2588219-B1 FILTER PLATE ARTICLE HAVING A WATER-ABSORBENT FILTER ASSEMBLY NEOGEN FOOD SAFETY US HOLDCO CORP (US) 2024-05-29 EP disclosed
US-11505816-B2 Medium for detecting Staphylococcus aureus, sheet for detecting S. aureus comprising same, and method for detecting S. aureus using same KIKKOMAN CORPORATION (JP) 2022-11-22 US disclosed
CN-108603215-B Culture medium for detecting staphylococcus aureus, staphylococcus aureus detection sheet having the same, and method for detecting staphylococcus aureus using the same 龟甲万株式会社 2022-10-14 CN disclosed
US-20210017566-A1 MEDIUM FOR DETECTING STAPHYLOCOCCUS AUREUS, SHEET FOR DETECTING S. AUREUS COMPRISING SAME, AND METHOD FOR DETECTING S. AUREUS USING SAME KIKKOMAN CORPORATION (JP) 2021-01-21 US disclosed
US-5958675-A Method for detecting bacteria using bacteriophage, contrast-coloring dye and precipitable dye 3M INNOVATIVE PROPERTIES COMPANY (US) 1999-09-28 US disclosed
WO-1998048042-A2 METHODS AND DEVICES FOR DETECTING BACTERIOPHAGE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-10-29 WO disclosed
EP-0775215-A1 CHEMILUMINESCENCE ASSAYS BASED ON INDOXYL SUBSTRATES, THIOINDOXYL SUBSTRATES AND OTHER SUBSTRATES MEDILITE DIAGNOSTIKA (US) 1997-05-28 EP disclosed
US-5589328-A CHEMICAL INTERMEDIATES OR METABOLITES FOR IMMUNOASSAY MEDILITE DIAGNOSTIKA 1996-12-31 US disclosed
WO-1996004400-A1 CHEMILUMINESCENCE ASSAYS BASED ON INDOXYL SUBSTRATES, THIOINDOXYL SUBSTRATES AND OTHER SUBSTRATES MEDILITE DIAGNOSTIKA (US) 1996-02-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030037387-A1 Phosphate dye precursors and use thereof for dyeing keratin fibres KRT18, ALPG, ALPP GPR84 3813/4885NR4A2 3703/4885ALDH1A1 397/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.