Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 4/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.35 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.34 |
| ▸ | ABAT | P80404 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL417139 | 0.78 | NISCH (0.45) | POLBL3MBTL1ALDH1A1HSD17B10NPC1 | |
| SCHEMBL415765 | 0.75 | MAPK1 (0.47) | POLBL3MBTL1ALDH1A1NPC1RAB9A | |
| SCHEMBL823787 | 0.75 | MAPK13 (0.43) | POLBL3MBTL1ALDH1A1NPC1RAB9A | |
| SCHEMBL7119605 | 0.75 | RPS6KA3 (0.45) | POLBL3MBTL1ALDH1A1HSD17B10NPC1 | |
| SCHEMBL416642 | 0.75 | POLB (0.56) | POLBL3MBTL1NPC1RAB9AKDM4E | |
| SCHEMBL2304276 | 0.75 | POLB (0.39) | POLBL3MBTL1NPC1RAB9AMAPT | |
| SCHEMBL7641810 | 0.74 | POLB (0.40) | POLBL3MBTL1NPC1RAB9A | |
| SCHEMBL416435 | 0.74 | POLB (0.60) | POLBL3MBTL1ALDH1A1NPC1RAB9A | |
| SCHEMBL10316101 | 0.74 | COMT (0.44) | POLBNPC1RAB9AKDM4E | |
| SCHEMBL17673753 | 0.73 | MMP2 (0.52) | POLBL3MBTL1ALDH1A1HSD17B10NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101679432-A | Heteroaryl compounds, compositions thereof, and their use as protein kinase inhibitors | SIGNAL PHARM LLC | 2010-03-24 | — | — | CN | disclosed |
| EP-2078018-A1 | HETEROARYL COMPOUNDS, COMPOSITIONS THEREOF, AND USE THEREOF AS PROTEIN KINASE INHIBITORS | Signal Pharmaceuticals LLC (US) | 2009-07-15 | — | — | EP | disclosed |
| WO-2008051494-A1 | HETEROARYL COMPOUNDS, COMPOSITIONS THEREOF, AND USE THEREOF AS PROTEIN KINASE INHIBITORS | SIGNAL PHARMACEUTICALS, LLC (US) | 2008-05-02 | — | — | WO | disclosed |
| EP-1260858-A2 | Image formation process | Fuji Photo Film Co., Ltd. (JP) | 2002-11-27 | — | — | EP | disclosed |
| US-6297000-B1 | IMAGING LAYERS WITH SILVER SALT, REDUCING AGENT AND BINDERS WITH UNSATURATED COMPOUNDS | FUJI PHOTO FILM CO., LTD. (JP) | 2001-10-02 | — | — | US | disclosed |
| EP-0713131-B1 | Silver halide photographic material | FUJI PHOTO FILM CO LTD (JP) | 2000-02-02 | — | — | EP | disclosed |
| US-5968725-A | MATERIAL COMPRISING ON SUPPORT SILVER HALIDE PHOTOSENSITIVE LAYER CONTAINING ORGANIC SILVER SALT, REDUCING AGENT, ULTRAHIGH CONTRAST PROMOTING AGENT, SELECTED HETEROCYCLIC MERCAPTO COMPOUND | FUJI PHOTO FILM CO., LTD. (JP) | 1999-10-19 | — | — | US | disclosed |
| US-5688630-A | CONTAINING A HYDRAZIDE COMPOUND | FUJI PHOTO FILM CO., LTD. (JP) | 1997-11-18 | — | — | US | disclosed |
| US-5667936-A | FLUOROMETHYLATED HYDRAZIDE, HIGH CONTRAST, PROCESSING STABILITY, PRESERVABILITY | FUJI PHOTO FILM CO., LTD. (JP) | 1997-09-16 | — | — | US | disclosed |
| EP-0736798-A1 | Silver halide photographic material | FUJI PHOTO FILM CO., LTD. (JP) | 1996-10-09 | — | — | EP | disclosed |
| EP-0713131-A2 | Silver halide photographic material | FUJI PHOTO FILM CO., LTD. (JP) | 1996-05-22 | — | — | EP | disclosed |
| US-5338658-A | Nucleation agent | FUJI PHOTO FILM CO., LTD. (JP) | 1994-08-16 | — | — | US | disclosed |
| EP-0276842-B1 | SILVER HALIDE PHOTOGRAPHIC MATERIAL | FUJI PHOTO FILM CO., LTD. (JP) | 1992-07-29 | — | — | EP | disclosed |
| US-5035993-A | Quaternary ammonium salt nucleating agent | FUJI PHOTO FILM CO., LTD. (JP) | 1991-07-30 | — | — | US | disclosed |
| US-4987052-A | REDUCED AMOUNT OF BLACK PEPPERS | FUJI PHOTO FILM CO., LTD. (JP) | 1991-01-22 | — | — | US | disclosed |
| US-4877723-A | EMULSION LAYER CONTAINING AN ALKYNYL-SUBSTITUTED HETEROCYCLIC QUATERNARY AMMONIUM SALT; DIRECT POSITIVES; REVERSAL | FUJI PHOTO FILM CO., LTD. (JP) | 1989-10-31 | — | — | US | disclosed |
| US-4859579-A | Silver halide photographic material | FUJI PHOTO FILM CO., LTD. (JP) | 1989-08-22 | — | — | US | disclosed |
| US-4828973-A | DIRECT POSITIVES WITH REVERSAL PROPERTIES | FUJI PHOTO FILM CO., LTD. (JP) | 1989-05-09 | — | — | US | disclosed |
| EP-0276842-A2 | Silver halide photographic material | FUJI PHOTO FILM CO., LTD. (JP) | 1988-08-03 | — | — | EP | disclosed |