Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.43 |
| ▸ | HPGDS | O60760 | 1/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.43 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.42 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.42 |
| ▸ | BTK | Q06187 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.39 |
| ▸ | RAF1 | P04049 | 1/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL416642 | 0.96 | POLB (0.56) | POLBL3MBTL1NPC1RAB9AGAA | |
| SCHEMBL419538 | 0.83 | DHODH (0.45) | POLBL3MBTL1NPC1RAB9AMAPK13 | |
| SCHEMBL384952 | 0.83 | NPC1 (0.61) | POLBL3MBTL1NPC1RAB9AGAA | |
| SCHEMBL417139 | 0.82 | NISCH (0.45) | POLBL3MBTL1NPC1RAB9AGAA | |
| SCHEMBL24317555 | 0.80 | NPC1 (0.59) | POLBL3MBTL1NPC1RAB9AGAA | |
| SCHEMBL420012 | 0.80 | MGAM (0.43) | POLBL3MBTL1NPC1RAB9AGAA | |
| SCHEMBL416478 | 0.79 | NR1I3 (0.50) | L3MBTL1NPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL417398 | 0.79 | DHODH (0.47) | POLBL3MBTL1NPC1MAPTHPGD | |
| SCHEMBL7119605 | 0.78 | RPS6KA3 (0.45) | POLBL3MBTL1NPC1RAB9AGAA | |
| SCHEMBL823787 | 0.78 | MAPK13 (0.43) | POLBL3MBTL1NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 170 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120022083-A1 | SMALL MOLECULE MODULATORS OF CELL ADHESION | ADHEREX TECHNOLOGIES, INC. (CA) | 2012-01-26 | — | — | US | claimed |
| US-20090291967-A1 | SMALL MOLECULE MODULATORS OF CELL ADHESION | ADHEREX TECHNOLOGIES, INC. (CA) | 2009-11-26 | — | — | US | claimed |
| EP-4097285-B1 | SUBSTITUTED THIOL MELT ADDITIVES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2024-06-26 | — | — | EP | disclosed |
| US-11873389-B2 | Composition and molded article | AKITA UNIVERSITY (JP) | 2024-01-16 | — | — | US | disclosed |
| US-20230357535-A1 | CROSSLINKABLE ELASTOMER COMPOSITION AND FLUORORUBBER MOLDED ARTICLE | DAIKIN INDUSTRIES, LTD. (JP) | 2023-11-09 | — | — | US | disclosed |
| WO-2023210818-A1 | COMPOSITION INCLUDING FLUORORUBBER | ダイキン工業株式会社 | 2023-11-02 | — | — | WO | disclosed |
| WO-2023195485-A1 | COMPOSITION AND CROSSLINKED PRODUCT | ダイキン工業株式会社 | 2023-10-12 | — | — | WO | disclosed |
| US-20230321091-A1 | SUBSTITUTED PYRIDAZINONES FOR USE IN THE TREATMENT OF NEUROMUSCULAR DISEASES | EDGEWISE THERAPEUTICS, INC. | 2023-10-12 | — | — | US | disclosed |
| US-20230321091-A1 | SUBSTITUTED PYRIDAZINONES FOR USE IN THE TREATMENT OF NEUROMUSCULAR DISEASES | EDGEWISE THERAPEUTICS, INC. | 2023-10-12 | — | — | US | disclosed |
| WO-2023189547-A1 | COMPOSITION, CROSSLINKED PRODUCT, AND SEALING MATERIAL | ダイキン工業株式会社 | 2023-10-05 | — | — | WO | disclosed |
| EP-4253432-A1 | FLUOROPOLYMER, AQUEOUS LIQUID DISPERSION, COMPOSITION, AND CROSSLINKED PRODUCT | DAIKIN INDUSTRIES, LTD. (JP) | 2023-10-04 | — | — | EP | disclosed |
| US-20070197513-A1 | Ion channel modulators | SCION PHARMACEUTICALS, INC. | 2007-08-23 | — | — | US | disclosed |
| US-20070197513-A1 | Ion channel modulators | SCION PHARMACEUTICALS, INC. | 2007-08-23 | — | — | US | disclosed |
| US-20070197619-A1 | Ion Channel Modulators | WYETH | 2007-08-23 | — | — | US | disclosed |
| US-20070197619-A1 | Ion Channel Modulators | WYETH | 2007-08-23 | — | — | US | disclosed |
| US-20070191448-A1 | Ion channel modulators | SCION PHARMACEUTICALS, INC. | 2007-08-16 | — | — | US | disclosed |
| US-20070191448-A1 | Ion channel modulators | SCION PHARMACEUTICALS, INC. | 2007-08-16 | — | — | US | disclosed |
| US-20070135467-A1 | HETEROCYCLIC CETP INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY | 2007-06-14 | — | — | US | disclosed |
| WO-2005097112-A2 | ION CHANNEL MODULATORS | WYETH (US) | 2005-10-20 | — | — | WO | disclosed |
| EP-0329357-A1 | Dihydropyridine anti-allergic and anti-inflammatory agents | Pfizer Limited (GB) | 1989-08-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230321091-A1 | SUBSTITUTED PYRIDAZINONES FOR USE IN THE TREATMENT OF NEUROMUSCULAR DISEASES | IL6, MUSK, SMN1; SMN2 | POLB 1354/4885L3MBTL1 3930/4885NPC1 4135/4885 |
| US-20070135467-A1 | HETEROCYCLIC CETP INHIBITORS | CETP, CES1, NPC1 | POLB 380/4885L3MBTL1 2178/4885NPC1 3/4885 |
| US-20070197619-A1 | Ion Channel Modulators | CACNA1B, CACNA1C, TRPV1 | POLB 4663/4885L3MBTL1 3558/4885NPC1 325/4885 |
| US-20070191448-A1 | Ion channel modulators | CACNA1B, CACNA1C, TRPV1 | POLB 4663/4885L3MBTL1 3558/4885NPC1 325/4885 |
| US-20090291967-A1 | SMALL MOLECULE MODULATORS OF CELL ADHESION | CDH1, EPCAM, ICAM1 | POLB 4824/4885L3MBTL1 2408/4885NPC1 3435/4885 |
| US-20120022083-A1 | SMALL MOLECULE MODULATORS OF CELL ADHESION | CDH1, EPCAM, ICAM1 | POLB 4824/4885L3MBTL1 2408/4885NPC1 3435/4885 |
| US-20070197513-A1 | Ion channel modulators | CACNA1B, CACNA1C, TRPV1 | POLB 4663/4885L3MBTL1 3558/4885NPC1 325/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.