Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | FLT4 | P35916 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGAV | P06756 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CASR | P41180 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CCR3 | P51677 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1205935 | 0.84 | MEN1 (0.42) | ROCK2SMN1; SMN2ITGB3ITGAVRAB9A | |
| SCHEMBL1204325 | 0.79 | ADRB2 (0.52) | ROCK2SMN1; SMN2ADRB2KMT2A | |
| SCHEMBL1206030 | 0.76 | ADRB2 (0.47) | SMN1; SMN2ITGB3ITGAVADRB2 | |
| SCHEMBL1206028 | 0.76 | ADRB2 (0.47) | SMN1; SMN2ITGB3ITGAVADRB2 | |
| SCHEMBL2824703 | 0.72 | ADRB2 (0.47) | SMN1; SMN2ADRB2 | |
| SCHEMBL2824699 | 0.72 | ADRB2 (0.47) | SMN1; SMN2ADRB2 | |
| SCHEMBL1205939 | 0.70 | ADRB2 (0.46) | SMN1; SMN2RAB9AADRB2KMT2ANPC1 | |
| SCHEMBL1205430 | 0.70 | ADRB2 (0.46) | SMN1; SMN2ADRB2 | |
| SCHEMBL1205434 | 0.70 | ADRB2 (0.46) | SMN1; SMN2ADRB2 | |
| SCHEMBL1206056 | 0.69 | ROCK2 (0.47) | ROCK2SMN1; SMN2HIF1ARAB9APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2096105-A1 | Derivatives of 4-(2-amino-1-hydroxyethyl)phenol as agonists of the b2 adrenergic receptor | Laboratorios Almirall, S.A. (ES) | 2009-09-02 | — | — | EP | disclosed |