Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | PRKDC | P78527 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | ERN1 | O75460 | 5/20 | 0.49 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.39 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31539517 | 0.84 | ALDH1A1 (0.46) | ALDH1A1MAPTKDM4EPRKDCCYP3A4 | |
| SCHEMBL6826066 | 0.84 | PKM (0.46) | ALDH1A1MAPTKDM4EPRKDCCYP3A4 | |
| SCHEMBL27841655 | 0.78 | CYP19A1 (0.58) | MAPTTLR9MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28842339 | 0.77 | NQO2 (0.42) | ALDH1A1MAPTKDM4EPRKDCCYP3A4 | |
| SCHEMBL4218188 | 0.77 | ALDH1A1 (0.58) | ALDH1A1MAPTKDM4EPRKDCCYP3A4 | |
| SCHEMBL31539526 | 0.76 | ALDH1A1 (0.40) | ALDH1A1MAPTKDM4EPRKDCCYP3A4 | |
| SCHEMBL15400557 | 0.76 | PKM (0.41) | ALDH1A1MAPTKDM4EPRKDCCYP3A4 | |
| SCHEMBL29708088 | 0.76 | ERN1 (0.56) | ALDH1A1MAPTKDM4EPRKDCCYP3A4 | |
| SCHEMBL5891799 | 0.76 | CYP3A4 (0.50) | ALDH1A1MAPTKDM4ECYP3A4ERN1 | |
| SCHEMBL594444 | 0.76 | ERN1 (0.56) | ALDH1A1MAPTKDM4EPRKDCCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7560491-B2 | Z-stilbenes derivatives and the pharmaceutical composition thereof | TAIPEI MEDICAL UNIVERSITY (TW) | 2009-07-14 | — | — | US | disclosed |
| US-7560491-B2 | Z-stilbenes derivatives and the pharmaceutical composition thereof | TAIPEI MEDICAL UNIVERSITY (TW) | 2009-07-14 | — | — | US | disclosed |
| US-7560491-B2 | Z-stilbenes derivatives and the pharmaceutical composition thereof | TAIPEI MEDICAL UNIVERSITY (TW) | 2009-07-14 | — | — | US | disclosed |
| US-20080096973-A1 | Z-stilbenes derivatives and the pharmaceutical composition thereof | TAIPEI MEDICAL UNIVERSITY (TW) | 2008-04-24 | — | — | US | disclosed |
| US-20080096973-A1 | Z-stilbenes derivatives and the pharmaceutical composition thereof | TAIPEI MEDICAL UNIVERSITY (TW) | 2008-04-24 | — | — | US | disclosed |
| US-20080096973-A1 | Z-stilbenes derivatives and the pharmaceutical composition thereof | TAIPEI MEDICAL UNIVERSITY (TW) | 2008-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080096973-A1 | Z-stilbenes derivatives and the pharmaceutical composition thereof | CCNB1, ZYX, H1-0 | ALDH1A1 924/4885MAPT 2591/4885KDM4E 2682/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.