Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.72 |
| ▸ | MEN1 | O00255 | 2/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.72 |
| ▸ | POLB | P06746 | 1/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.67 |
| ▸ | NPC1 | O15118 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | HPGDS | O60760 | 1/20 | 0.59 |
| ▸ | ESRRG | P62508 | 3/20 | 0.58 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.58 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.56 |
| ▸ | DAO | P14920 | 1/20 | 0.55 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.54 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3576074 | 0.98 | RAB9A (0.70) | RAB9AMEN1KMT2APOLBKDM4E | |
| SCHEMBL27983242 | 0.88 | RAB9A (0.67) | RAB9AMEN1KMT2APOLBKDM4E | |
| SCHEMBL16595405 | 0.87 | RAB9A (0.61) | RAB9AMEN1KMT2APOLBKDM4E | |
| SCHEMBL2715877 | 0.85 | RAB9A (0.63) | RAB9AMEN1KMT2APOLBKDM4E | |
| SCHEMBL27358085 | 0.85 | IKBKB (0.69) | RAB9AMEN1KMT2APOLBKDM4E | |
| SCHEMBL2491267 | 0.84 | RAB9A (1.00) | RAB9AMEN1KMT2APOLBKDM4E | |
| SCHEMBL10963422 | 0.84 | RAB9A (0.72) | RAB9AMEN1KMT2APOLBKDM4E | |
| SCHEMBL2083801 | 0.84 | MEN1 (0.72) | RAB9AMEN1KMT2APOLBKDM4E | |
| SCHEMBL29906336 | 0.84 | RAB9A (0.79) | RAB9AMEN1KMT2APOLBKDM4E | |
| SCHEMBL3749139 | 0.84 | HPGDS (0.69) | RAB9AMEN1KMT2APOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105461680-B | A kind of synthetic method of 2- (4- fluorophenyls) thiophene | 苏州毕奇尔生物科技有限公司 | 2018-06-22 | — | — | CN | claimed |
| CN-105461680-A | Synthetic method of 2-(4-fluorophenyl) thiophene | SUZHOU BICHAL BIOTECHNOLOGY CO LTD | 2016-04-06 | — | — | CN | claimed |
| US-20090170913-A1 | NOVEL MCH RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY | 2009-07-02 | — | — | US | claimed |
| EP-1828177-B1 | NOVEL MCH RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 2008-08-13 | — | — | EP | claimed |
| US-7109243-B2 | Inhibitors of cathepsin S | IRM LLC (BM) | 2006-09-19 | — | — | US | claimed |
| EP-1237849-A1 | ACTIVATORS OF SOLUBLE GUANYLATE CYCLASE | UNIVERSITY COLLEGE LONDON (GB) | 2002-09-11 | — | — | EP | claimed |
| WO-2001032604-A1 | ACTIVATORS OF SOLUBLE GUANYLATE CYCLASE | UNIVERSITY COLLEGE LONDON (GB) | 2001-05-10 | — | — | WO | claimed |
| US-20220202772-A1 | COMPOSITIONS AND METHODS FOR INHIBITING RIBOSOME INACTIVATING PROTEINS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2022-06-30 | — | — | US | disclosed |
| US-11269251-B2 | Resist composition and patterning process | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2022-03-08 | — | — | US | disclosed |
| EP-2607348-B1 | Plasminogen Activator Inhibitor-1 Inhibitor | RENASCIENCE INC (JP) | 2021-03-17 | — | — | EP | disclosed |
| CN-109868134-A | A kind of particle and preparation method thereof | TCL集团股份有限公司 | 2019-06-11 | — | — | CN | disclosed |
| CN-109868133-A | A kind of particle and preparation method thereof | TCL集团股份有限公司 | 2019-06-11 | — | — | CN | disclosed |
| CN-109868132-A | A kind of particle and preparation method thereof | TCL集团股份有限公司 | 2019-06-11 | — | — | CN | disclosed |
| WO-2001032604-A1 | ACTIVATORS OF SOLUBLE GUANYLATE CYCLASE | UNIVERSITY COLLEGE LONDON (GB) | 2001-05-10 | — | — | WO | disclosed |
| WO-2001025229-A1 | AMIDE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-04-12 | — | — | WO | disclosed |
| EP-0259972-B1 | HETEROCYCLIC PROPENE AMIDE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS PHARMACEUTICALS | LILLY INDUSTRIES LIMITED (GB) | 1993-07-14 | — | — | EP | disclosed |
| CN-1021050-C | PREPARING METHOD FOR BUTYRUMID DERIVATIVE | LILLY INDUSTRIES LTD (GB) | 1993-06-02 | — | — | CN | disclosed |
| CN-1059142-A | New thiophene derivant | FUJISAWA PHARMACEUTICAL CO (JP) | 1992-03-04 | — | — | CN | disclosed |
| CN-87105515-A | Derivatives of phenylbutenamide compounds and preparation method thereof | — | 1988-03-23 | — | — | CN | disclosed |
| EP-0259972-A2 | Heterocyclic propene amide derivatives, processes for their preparation and their use as pharmaceuticals | LILLY INDUSTRIES LIMITED (GB) | 1988-03-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220202772-A1 | COMPOSITIONS AND METHODS FOR INHIBITING RIBOSOME INACTIVATING PROTEINS | RACK1, RRBP1, RPL30 | RAB9A 1823/4885MEN1 4218/4885KMT2A 2968/4885 |
| US-20090170913-A1 | NOVEL MCH RECEPTOR ANTAGONISTS | MCHR1, MCHR2, MC1R | RAB9A 1154/4885MEN1 550/4885KMT2A 1012/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.