Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 15/20 | 0.44 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4225350 | 0.95 | UTS2R (0.42) | UTS2RJAK3BTKROCK2ROCK1 | |
| SCHEMBL2383826 | 0.88 | CTSK (0.41) | UTS2R | |
| SCHEMBL2383763 | 0.86 | UTS2R (0.47) | UTS2RHDAC1 | |
| SCHEMBL4377779 | 0.85 | UTS2R (0.52) | UTS2RROCK2ROCK1 | |
| SCHEMBL4219227 | 0.85 | UTS2R (0.42) | UTS2RROCK2ROCK1 | |
| SCHEMBL3226314 | 0.85 | UTS2R (0.42) | UTS2RROCK2ROCK1 | |
| SCHEMBL3218967 | 0.85 | UTS2R (0.42) | UTS2RROCK2ROCK1 | |
| SCHEMBL4223976 | 0.85 | POLB (0.40) | — | |
| SCHEMBL3234560 | 0.83 | UTS2R (0.43) | UTS2RROCK2ROCK1 | |
| SCHEMBL3222714 | 0.83 | UTS2R (0.39) | UTS2RHDAC1ROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2135620-A1 | OCULAR HYPOTENSIVE AGENT COMPRISING COMPOUND CAPABLE OF INHIBITING HISTONE DEACETYLASE AS ACTIVE INGREDIENT | Santen Pharmaceutical Co., Ltd (JP) | 2009-12-23 | — | — | EP | disclosed |
| EP-2133339-A1 | NOVEL (2-AMINOPHENYL)PYRIDINECARBOXAMIDE DERIVATIVE HAVING UREA STRUCTURE | Santen Pharmaceutical Co., Ltd (JP) | 2009-12-16 | — | — | EP | disclosed |