Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 13/20 | 0.42 |
| ▸ | CNR2 | P34972 | 12/20 | 0.42 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4203003 | 0.87 | LIPG (0.49) | CNR1CNR2LIPGKMT2ANAMPT | |
| SCHEMBL4056225 | 0.85 | KMT2A (0.45) | CNR1CNR2LIPGKMT2ANAMPT | |
| SCHEMBL4225048 | 0.81 | KMT2A (0.41) | CNR1CNR2KMT2ANAMPT | |
| SCHEMBL4055907 | 0.78 | NAMPT (0.44) | CNR1CNR2NAMPT | |
| SCHEMBL4225047 | 0.73 | NAMPT (0.35) | CNR1CNR2KMT2ANAMPT | |
| SCHEMBL823466 | 0.69 | PIK3CD (0.44) | CNR1CNR2LIPGKMT2A | |
| SCHEMBL4046865 | 0.69 | CD274 (0.49) | CNR2KMT2A | |
| SCHEMBL823442 | 0.68 | KCNH2 (0.45) | LIPG | |
| SCHEMBL6077256 | 0.68 | LIPG (0.79) | LIPG | |
| SCHEMBL6094568 | 0.68 | LMNA (0.51) | CNR1CNR2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1758585-A4 | HIV INTEGRASE INHIBITORS | MERCK & CO INC (US) | 2009-07-22 | — | — | EP | claimed |
| EP-1758585-A2 | HIV INTEGRASE INHIBITORS | Merck & Co., Inc. (US) | 2007-03-07 | — | — | EP | claimed |
| WO-2005120516-A2 | HIV INTEGRASE INHIBITORS | MERCK & CO., INC. (US) | 2005-12-22 | — | — | WO | claimed |