Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 14/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 12/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 8/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | TYMS | P04818 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4226665 | 1.00 | CYP19A1 (0.44) | CYP19A1CYP11B2CYP11B1TDP1L3MBTL1 | |
| SCHEMBL13229260 | 0.92 | CYP19A1 (0.41) | CYP19A1CYP11B2CYP11B1TDP1L3MBTL1 | |
| SCHEMBL4231848 | 0.89 | CYP19A1 (0.56) | CYP19A1CYP11B2CYP11B1PARP10 | |
| SCHEMBL4231849 | 0.89 | CYP19A1 (0.56) | CYP19A1CYP11B2CYP11B1PARP10 | |
| SCHEMBL4234962 | 0.83 | CYP19A1 (0.48) | CYP19A1CYP11B2CYP11B1PARP1PARP10 | |
| SCHEMBL4234960 | 0.83 | CYP19A1 (0.48) | CYP19A1CYP11B2CYP11B1PARP1PARP10 | |
| SCHEMBL4226486 | 0.83 | CYP11B2 (0.44) | CYP19A1CYP11B2CYP11B1PARP1PARP10 | |
| SCHEMBL4226487 | 0.83 | CYP11B2 (0.44) | CYP19A1CYP11B2CYP11B1PARP1PARP10 | |
| SCHEMBL13229552 | 0.80 | TYRO3 (0.37) | CYP19A1CYP11B2CYP11B1PARP10MAOB | |
| SCHEMBL4221234 | 0.80 | CYP19A1 (0.57) | CYP19A1CYP11B2CYP11B1MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090105278-A1 | Selective inhibitors of human corticosteroid syntheses | UNIVERSITAT DES SAARLANDES (DE) | 2009-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105278-A1 | Selective inhibitors of human corticosteroid syntheses | HSD11B1, HSD11B2, CYP11B1 | CYP19A1 76/4885CYP11B2 5/4885CYP11B1 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.