Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Demannose. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Demannose SCHEMBL19691965 | 1.00 | LMNA (0.44) | LMNAL3MBTL1TDP1PDE4AUSP2 | |
| Demannose SCHEMBL27674763 | 1.00 | LMNA (0.44) | LMNAL3MBTL1TDP1PDE4AUSP2 | |
| Demannose SCHEMBL31412690 | 1.00 | LMNA (0.44) | LMNAL3MBTL1TDP1PDE4AUSP2 | |
| Demannose SCHEMBL28513575 | 0.98 | LMNA (0.42) | LMNAL3MBTL1TDP1PDE4AUSP2 | |
| Demannose SCHEMBL10423685 | 0.96 | LMNA (0.41) | LMNAL3MBTL1TDP1PDE4AUSP2 | |
| Demannose SCHEMBL25263022 | 0.92 | LMNA (0.44) | LMNAL3MBTL1TDP1PDE4AUSP2 | |
| Demannose SCHEMBL16234821 | 0.92 | LMNA (0.44) | LMNAL3MBTL1TDP1PDE4AUSP2 | |
| Demannose SCHEMBL7715623 | 0.92 | LMNA (0.44) | LMNAL3MBTL1TDP1PDE4AUSP2 | |
| Demannose SCHEMBL27827379 | 0.92 | LMNA (0.44) | LMNAL3MBTL1TDP1PDE4AUSP2 | |
| Demannose SCHEMBL25263020 | 0.92 | LMNA (0.44) | LMNAL3MBTL1TDP1PDE4AUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3098591-A | — | — | None | — | — | JP | disclosed |
| EP-4441213-A2 | FUNGAL PROTEASES, TREATED COMPOSITIONS, AND USES THEREOF | Shared-X LLC (US) | 2024-10-09 | — | — | EP | disclosed |
| WO-2023102551-A2 | FUNGAL PROTEASES, TREATED COMPOSITIONS, AND USES THEREOF | SHARED-X LLC (US) | 2023-06-08 | — | — | WO | disclosed |
| US-20220332658-A1 | BIOLOGICAL CONTROL AGENT FORMULATIONS INCLUDING TRICHODERMA | SHARED-X LLC (KY) | 2022-10-20 | — | — | US | disclosed |
| CN-105624076-B | Acidproof denitrifying bacillus subtilis and complex micro organism fungicide and preparation method | 山东康地得生物开发有限公司 | 2019-02-15 | — | — | CN | disclosed |
| CN-104830724-B | One plant of rhizobium strains and its application | 浙江省环境保护科学设计研究院 | 2018-01-23 | — | — | CN | disclosed |
| CN-105624076-A | Acid-resistant denitrifying Bacillus subtilis strain, and composite microbial inoculant and preparation method thereof | SHANDONG KANGDIDE BIOLOGICAL DEV CO LTD | 2016-06-01 | — | — | CN | disclosed |
| CN-103875893-B | Many bacterial classifications composite microbial feed additive and preparation method thereof | DONGGUAN TIANSHENG BIOTECHNOLOGY CO., LTD. (CN) | 2016-05-04 | — | — | CN | disclosed |
| CN-104830724-A | Rhizobium strain and application thereof | ENVIRONMENTAL SCIENCE RES & DESIGN INST ZHEJIANG P | 2015-08-12 | — | — | CN | disclosed |
| CN-102701450-B | Method for restoring surface water by utilizing discarded plant leaves | UNIV SHANGHAI | 2014-09-10 | — | — | CN | disclosed |
| US-4504580-A | Antibiotics produced by fermentation of a novel strain of Streptomyces hygroscopicus | BRISTOL-MYERS COMPANY (US) | 1985-03-12 | — | — | US | disclosed |
| US-4468386-A | 1-Deamino-1-hydroxy-aminoglycoside compounds, antibacterial compositions and method of use | BRISTOL-MYERS COMPANY (US) | 1984-08-28 | — | — | US | disclosed |
| US-4450234-A | ANTIPROTOZOA, ANTITUMOR AGENT | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1984-05-22 | — | — | US | disclosed |
| US-4373028-A | ANTIBIOTIC C-14482 A1 | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1983-02-08 | — | — | US | disclosed |
| US-4331598-A | ANTITUMOR AND ANTIPROTOZOA AGENTS; ANTIBIOTICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1982-05-25 | — | — | US | disclosed |
| US-4320199-A | Fermentation process for producing nocardicins A and B | BRISTOL-MYERS COMPANY (US) | 1982-03-16 | — | — | US | disclosed |
| US-4298600-A | CULTURE PRODUCT OF NOCARDIA | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-11-03 | — | — | US | disclosed |
| US-4292309-A | CULTURE PRODUCT OF NOCARDIA | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-09-29 | — | — | US | disclosed |
| US-3960662-A | USING DEACYLATING ENZYME DERIVED FROM COMAMONAS | TOYO JOZO KABUSHIKI KAISHA (JA) | 1976-06-01 | — | — | US | disclosed |
| JP-H00398591-A | — | — | 0001-01-01 | — | — | JP | disclosed |