Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | CRHR1 | P34998 | 5/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4219437 | 0.79 | ALDH1A1 (0.35) | ALDH1A1NPSR1MAPTPOLBHTT | |
| SCHEMBL4222761 | 0.79 | ALDH1A1 (0.35) | ALDH1A1NPSR1MAPTPOLBHTT | |
| SCHEMBL4221217 | 0.76 | ALDH1A1 (0.33) | ALDH1A1NPSR1MAPTPOLBHTT | |
| SCHEMBL5790127 | 0.74 | ALDH1A1 (0.37) | ALDH1A1NPSR1MAPTPOLBHTT | |
| SCHEMBL16834246 | 0.74 | ALDH1A1 (0.37) | ALDH1A1NPSR1MAPTPOLBHTT | |
| Hydrochloric Acid SCHEMBL2796754 | 0.72 | ALDH1A1 (0.36) | ALDH1A1NPSR1MAPTPOLBHTT | |
| Hydrochloric Acid SCHEMBL2796752 | 0.72 | ALDH1A1 (0.36) | ALDH1A1NPSR1MAPTPOLBHTT | |
| SCHEMBL29713642 | 0.69 | ALDH1A1 (0.34) | ALDH1A1NPSR1MAPTPOLBHTT | |
| SCHEMBL1662433 | 0.69 | ALDH1A1 (0.34) | ALDH1A1NPSR1MAPTPOLBHTT | |
| SCHEMBL2796756 | 0.69 | ALDH1A1 (0.34) | ALDH1A1NPSR1MAPTPOLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090069569-A1 | CYCLOADDITION OF AZIDES AND ALKYNES | INSTITUT CATALA D'INVESTIGACIO QUIMICA (ES) | 2009-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069569-A1 | CYCLOADDITION OF AZIDES AND ALKYNES | PF4, AFF4, FLI1 | ALDH1A1 540/4885NPSR1 1518/4885MAPT 4537/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.