SCHEMBL4227086

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3816674	0.85	CYP3A4 (0.38)	CHRM5ADRA2CCYP3A4TSHRTDP1
	SCHEMBL4702124	0.85	CYP3A4 (0.38)	CHRM5ADRA2CCYP3A4TSHRTDP1
	SCHEMBL2687448	0.82	CYP3A4 (0.40)	CYP3A4TSHRTDP1MAPTAPEX1
	SCHEMBL8506958	0.78	CHRM5 (0.45)	CHRM5ADRA2CCHRM2CHRM4CHRM1
	SCHEMBL892512	0.74	CHRM5 (0.41)	CHRM5ADRA2C
	Trifluoroacetic Acid SCHEMBL3818811	0.74	DPP4 (0.34)	CYP3A4TSHRTDP1MAPTAPEX1
	SCHEMBL6258023	0.73	CYP3A4 (0.45)	CYP3A4TSHRTDP1MAPTAPEX1
	SCHEMBL318757	0.72	—	—
	SCHEMBL9255336	0.72	—	—
	SCHEMBL16190279	0.72	—	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.