Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGPS1 | O95749 | 3/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TYMP | P19971 | 1/20 | 0.35 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KDM5A | P29375 | 2/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.33 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.33 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.33 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | KCND3 | Q9UK17 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15296528 | 0.94 | GGPS1 (0.50) | GGPS1USP2LMNAKDM4EL3MBTL1 | |
| SCHEMBL13169271 | 0.92 | GGPS1 (0.53) | GGPS1USP2LMNAKDM4EDUSP3 | |
| SCHEMBL18935656 | 0.92 | GGPS1 (0.53) | GGPS1USP2LMNAKDM4EDUSP3 | |
| SCHEMBL9614232 | 0.92 | GGPS1 (0.53) | GGPS1USP2LMNAKDM4EDUSP3 | |
| SCHEMBL8871358 | 0.92 | GGPS1 (0.53) | GGPS1USP2LMNAKDM4EDUSP3 | |
| SCHEMBL27279849 | 0.90 | GGPS1 (0.43) | GGPS1USP2LMNAKDM4EL3MBTL1 | |
| Hydrochloric Acid SCHEMBL4583393 | 0.90 | GGPS1 (0.51) | GGPS1USP2LMNAKDM4EL3MBTL1 | |
| SCHEMBL17933337 | 0.89 | GGPS1 (0.47) | GGPS1KDM4EL3MBTL1KDM5AKDM4C | |
| SCHEMBL10283826 | 0.86 | KCNA5 (0.38) | GGPS1USP2LMNAKDM4EL3MBTL1 | |
| SCHEMBL25685114 | 0.84 | KDM4E (0.41) | GGPS1LMNAKDM4EL3MBTL1TYMP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7977351-B2 | Heteroaryl dihydroindolones as kinase inhibitors | ALLERGAN, INC. (US) | 2011-07-12 | — | — | US | disclosed |
| US-7595411-B2 | Phospholipid-analogous compounds | MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V. (DE) | 2009-09-29 | — | — | US | disclosed |
| US-20080045526-A1 | HETEROARYL DIHYDROINDOLONES AS KINASE INHIBITORS | ALLERGAN, INC. | 2008-02-21 | — | — | US | disclosed |
| US-20050165245-A1 | Phospholipid-analogous compounds | MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) | 2005-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080045526-A1 | HETEROARYL DIHYDROINDOLONES AS KINASE INHIBITORS | REN, JAK2, ABL1 | GGPS1 2317/4885USP2 4158/4885LMNA 3077/4885 |
| US-20050165245-A1 | Phospholipid-analogous compounds | PHOSPHO1, SGMS1, SGMS2 | GGPS1 120/4885USP2 4062/4885LMNA 1352/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.