Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL423921 | 0.92 | TSHR (0.49) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL422877 | 0.88 | TSHR (0.63) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL426982 | 0.86 | TSHR (0.45) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL420653 | 0.86 | TSHR (0.57) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL420649 | 0.85 | TSHR (0.55) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL423893 | 0.85 | TSHR (0.55) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL424013 | 0.85 | TSHR (0.49) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| Acrylic Acid Ethyl Ester SCHEMBL340906 | 0.84 | TSHR (0.40) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL237172 | 0.81 | TSHR (0.68) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL424629 | 0.81 | THRB (0.44) | TSHRHPGDALDH1A1CYP3A4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8940834-B2 | Partially aromatic polyamide moulding compositions and their uses | EMS-PATENT AG (CH) | 2015-01-27 | — | — | US | claimed |
| EP-2410020-B1 | Partially aromatic polyamide moulding compositions and their applications | EMS PATENT AG (CH) | 2013-01-30 | — | — | EP | claimed |
| US-20120022194-A1 | PARTIALLY AROMATIC POLYAMIDE MOULDING COMPOSITIONS AND THEIR USES | EMS-PATENT AG (CH) | 2012-01-26 | — | — | US | claimed |
| US-8940834-B2 | Partially aromatic polyamide moulding compositions and their uses | EMS-PATENT AG (CH) | 2015-01-27 | — | — | US | disclosed |
| US-20120022194-A1 | PARTIALLY AROMATIC POLYAMIDE MOULDING COMPOSITIONS AND THEIR USES | EMS-PATENT AG (CH) | 2012-01-26 | — | — | US | disclosed |