⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8674156 | 0.81 | — | — | |
| SCHEMBL12475458 | 0.75 | LMNA (0.30) | — | |
| SCHEMBL210738 | 0.70 | — | — | |
| SCHEMBL1006848 | 0.67 | — | — | |
| SCHEMBL242829 | 0.67 | — | — | |
| SCHEMBL4595691 | 0.67 | TRPA1 (0.32) | — | |
| SCHEMBL1895421 | 0.67 | — | — | |
| SCHEMBL247513 | 0.67 | — | — | |
| SCHEMBL11598290 | 0.67 | — | — | |
| SCHEMBL42915 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 204 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2595948-B1 | A METHOD OF PRODUCING INGENOL-3-ANGELATE | LEO LABORATORIES LTD (IE) | 2019-09-04 | — | — | EP | claimed |
| US-20160280627-A1 | METHOD OF PRODUCING INGENOL-3-ANGELATE | LEO LABORATORIES LIMITED (IE) | 2016-09-29 | — | — | US | claimed |
| US-9416084-B2 | Method of producing ingenol-3-angelate | LEO LABORATORIES LIMITED (IE) | 2016-08-16 | — | — | US | claimed |
| US-20150315118-A1 | METHOD OF PRODUCING INGENOL-3-ANGELATE | LEO LABORATORIES LIMITED (IE) | 2015-11-05 | — | — | US | claimed |
| US-8901356-B2 | Method of producing ingenol-3-angelate | LEO LABORATORIES LIMITED (IE) | 2014-12-02 | — | — | US | claimed |
| US-20130177952-A1 | METHOD OF PRODUCING INGENOL-3-ANGELATE | Hogberg, Thomas (DK) | 2013-07-11 | — | — | US | claimed |
| EP-2595948-A1 | A METHOD OF PRODUCING INGENOL-3-ANGELATE | LEO LABORATORIES LIMITED (IE) | 2013-05-29 | — | — | EP | claimed |
| WO-2012010172-A1 | A METHOD OF PRODUCING INGENOL-3-ANGELATE | LEO PHARMA A/S (DK) | 2012-01-26 | — | — | WO | claimed |
| CN-118339199-A | Gas phase process for preparing polypropylene random copolymer | 格雷斯公司 | 2024-07-12 | — | — | CN | disclosed |
| CN-118055955-A | Process for producing polyolefin granular resins with increased settled bulk density | 格雷斯公司 | 2024-05-17 | — | — | CN | disclosed |
| EP-4326036-A2 | ORGANIC ELECTROLUMINESCENT ELEMENT | UDC Ireland Limited (IE) | 2024-02-21 | — | — | EP | disclosed |
| EP-3389110-B1 | ORGANIC ELECTROLUMINESCENT ELEMENT | UDC IRELAND LTD (IE) | 2023-12-27 | — | — | EP | disclosed |
| EP-4223802-A2 | POLYMERIZATION CATALYST | Univation Technologies, LLC (US) | 2023-08-09 | — | — | EP | disclosed |
| EP-2953985-B1 | PREPARATION OF POLYOLEFIN | UNIVATION TECH LLC (US) | 2023-06-07 | — | — | EP | disclosed |
| CN-1165151-A | Process for production of long-chain branched polyolefins | UNION CARBIDE CHEM PLASTIC (US) | 1997-11-19 | — | — | CN | disclosed |
| EP-0805824-A1 | A SUPPORTED CATALYTIC ACTIVATOR | W.R. Grace & Co.-Conn. (US) | 1997-11-12 | — | — | EP | disclosed |
| WO-1996023005-A1 | A SUPPORTED CATALYTIC ACTIVATOR | W.R. GRACE & CO.-CONN. (US) | 1996-08-01 | — | — | WO | disclosed |
| WO-1996013532-A1 | IN SITU DEHYDROXYLATION OF SUPPORTS AND PREPARATION OF SUPPORTED METALLOCENE POLYOLEFIN CATALYSTS | W.R. GRACE & CO.-CONN. (US) | 1996-05-09 | — | — | WO | disclosed |
| US-5491167-A | INHIBITORS OF CHOLESTEROL BIOSYNTHESIS | SANKYO COMPANY, LIMITED (JP) | 1996-02-13 | — | — | US | disclosed |
| EP-0609058-A2 | Hexahydronaphthalene ester derivatives, their preparation and their therapeutic uses | SANKYO COMPANY LIMITED (JP) | 1994-08-03 | — | — | EP | disclosed |