Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 4/20 | 0.57 |
| ▸ | CTSK | P43235 | 4/20 | 0.57 |
| ▸ | CTSL | P07711 | 2/20 | 0.57 |
| ▸ | CTSB | P07858 | 1/20 | 0.57 |
| ▸ | REN | P00797 | 10/20 | 0.54 |
| ▸ | AKT1 | P31749 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ACE | P12821 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4216395 | 0.97 | CTSS (0.57) | CTSSCTSKCTSLCTSBREN | |
| SCHEMBL4231466 | 0.92 | CTSS (0.59) | CTSSCTSKCTSLCTSBREN | |
| SCHEMBL4231469 | 0.92 | CTSS (0.59) | CTSSCTSKCTSLCTSBREN | |
| SCHEMBL13878742 | 0.89 | CTSK (0.56) | CTSSCTSKCTSLCTSBREN | |
| SCHEMBL4218853 | 0.89 | CTSS (0.58) | CTSSCTSKCTSLCTSBREN | |
| SCHEMBL4219024 | 0.89 | CTSS (0.58) | CTSSCTSKCTSLCTSBREN | |
| SCHEMBL4219131 | 0.89 | CTSS (0.58) | CTSSCTSKCTSLCTSBREN | |
| SCHEMBL13878740 | 0.87 | CTSK (0.55) | CTSSCTSKCTSLCTSBREN | |
| SCHEMBL13878738 | 0.86 | CTSK (0.52) | CTSSCTSKCTSLCTSBREN | |
| SCHEMBL29477237 | 0.86 | CTSK (0.67) | CTSSCTSKCTSLCTSBAKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090105091-A1 | Modified Amino Acids | TECHNISCHE UNIVERSITAT WIEN (AT) | 2009-04-23 | — | — | US | disclosed |
| US-20090105091-A1 | Modified Amino Acids | TECHNISCHE UNIVERSITAT WIEN (AT) | 2009-04-23 | — | — | US | disclosed |
| US-20090105091-A1 | Modified Amino Acids | TECHNISCHE UNIVERSITAT WIEN (AT) | 2009-04-23 | — | — | US | disclosed |
| EP-1989180-A1 | MODIFIED AMINO ACIDS | Technische Universität Wien (AT) | 2008-11-12 | — | — | EP | disclosed |
| WO-2007095980-A1 | MODIFIED AMINO ACIDS | TECHNISCHE UNIVERSITÄT WIEN (AT) | 2007-08-30 | — | — | WO | disclosed |
| EP-1826199-A1 | Modified amino acids | Technische Universität Wien (AT) | 2007-08-29 | — | — | EP | disclosed |
| EP-1826199-A1 | Modified amino acids | Technische Universität Wien (AT) | 2007-08-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105091-A1 | Modified Amino Acids | SLC1A2, NR1H4, OXGR1 | CTSS 4519/4885CTSK 4083/4885CTSL 4417/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.