SCHEMBL4229

SCHEMBL4229

FC(F)(F)c1ccc(CBr)cc1

nearest known ligand 0.54

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.54
IDO1 P14902 4/20 0.52
PTPN1 P18031 1/20 0.48
GSK3B P49841 1/20 0.48
MAOB P27338 2/20 0.47
ALDH1A1 P00352 3/20 0.45
KDM4E B2RXH2 1/20 0.45
KIF11 P52732 2/20 0.44
KMT2A Q03164 1/20 0.44
MIF P14174 1/20 0.44
TSHR P16473 2/20 0.43
TRPA1 O75762 1/20 0.43
SRD5A2 P31213 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL28278225 0.97 TAAR1 (0.52) TAAR1IDO1PTPN1GSK3BMAOB
SCHEMBL2273601 0.93 MAOB (0.57) TAAR1IDO1PTPN1GSK3BMAOB
SCHEMBL22398395 0.87 AHR (0.52) TAAR1IDO1MAOB
SCHEMBL22398393 0.87 AHR (0.52) TAAR1IDO1MAOB
SCHEMBL3235897 0.87 MAPK14 (0.48) TAAR1IDO1MAOBKMT2A
SCHEMBL2651355 0.87 MAOB (0.52) TAAR1IDO1PTPN1GSK3BMAOB
SCHEMBL7010433 0.84 SRD5A2 (0.65) PTPN1GSK3BMAOBSRD5A2
SCHEMBL507252 0.84 BCHE (0.50) TAAR1IDO1PTPN1GSK3BKIF11
SCHEMBL28461107 0.82 ALDH1A1 (0.45) TAAR1IDO1PTPN1GSK3BMAOB
SCHEMBL17281438 0.81 TSHR (0.46) TAAR1IDO1ALDH1A1KMT2ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3700 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4724442-A1 AGONISM-ANTAGONISM IN ENDOSOMAL TLRS BY MODULATING CHEMICAL FEATURES IN 8-OXOPURINE: PROCESS FOR PREPARATION AND APPLICATION THEREOF Council of Scientific and Industrial Research (IN) 2026-04-15 EP claimed
US-12404245-B2 Process for the preparation of (R)-4-(1-(6-(4-(trifluoromethyl)benzyl)-6-azaspiro[2.5]octane-5-carboxamido)-cyclopropyl) benzoic acid or a salt thereof ROTTAPHARM BIOTECH S.R.L. (IT) 2025-09-02 US claimed
US-12304917-B1 Pleuromutilin derivative containing a thiazolo[5,4-c]pyridine side chain, and a preparation method and application thereof SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2025-05-20 US claimed
US-12275734-B1 Pleuromutilin onium salt derivative containing a 3H-imidazo[4,5-c]pyridine side chain, and a preparation method and application thereof SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2025-04-15 US claimed
CN-119684252-A Synthesis method of carbon dioxide-based cyclic carbonate 福建久策气体股份有限公司 2025-03-25 CN claimed
CN-119684271-A Indole-azole derivative WM-20, preparation method and application thereof 云南省中医医院(云南中医药大学第一附属医院) 2025-03-25 CN claimed
CN-119431278-A Aromatic oxetanes and their use in encapsulation compositions 华为技术有限公司 2025-02-14 CN claimed
CN-119264013-A Preparation method of (1-arylmethyl-3-aryl-1-trifluoromethyl propyl) aromatic compound 南京工业大学 2025-01-07 CN claimed
CN-119101052-A Matrine-triazole derivative and synthesis method thereof 吉林医药学院 2024-12-10 CN claimed
CN-118652422-A High-purity high-temperature-resistant anti-aging low-dielectric polyphenyl ether and preparation method thereof 四川大学 2024-09-17 CN claimed
CN-104181772-A Two-photon active photoacid generators taking biphenyl as conjugated structure and preparation method and application of two-photon active photoacid generators UNIV TONGJI 2014-12-03 CN claimed
CN-100569746-C Arylbis (perfluoroalkylsulfonyl) methane and metal salts thereof, and process for producing the same JAPAN SCIENCE & TECH AGENCY (JP) 2009-12-16 CN claimed
EP-1344772-B1 ARYLBIS (PERFLUOROALKYLSULFONYL) METHANE, METAL SALT OF THE SAME, AND PROCESSES FOR PRODUCING THESE JAPAN SCIENCE & TECH AGENCY (JP) 2009-07-22 EP claimed
US-7339082-B2 Arylbis (perfluoroalkylsulfonyl)methane and metallic salt thereof, and methods for producing the same JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) 2008-03-04 US claimed
US-20050070741-A1 Arylbis (perfluoroalkylsulfonyl)methane and metallic salt thereof, and methods for producing the same ISHIHARA KAZUAKI (JP) 2005-03-31 US claimed
CN-1481357-A Arylbis (perfluoroalkylsulfonyl) methane and metal salts thereof, and process for producing the same 科学技术振兴事业团 2004-03-10 CN claimed
US-20040030192-A1 Arylbis(perfluoroalkylsulfonyl) methane and metallic salt thereof and methods for producing the same JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2004-02-12 US claimed
EP-1344772-A1 ARYLBIS (PERFLUOROALKYLSULFONYL) METHANE, METAL SALT OF THE SAME, AND PROCESSES FOR PRODUCING THESE Japan Science and Technology Corporation (JP) 2003-09-17 EP claimed
WO-2003011917-A1 METHOD OF CURING ELASTOMERS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2003-02-13 WO claimed
EP-0440329-A1 S-substituted carbonyl substituted betathioacrylamide biocides and fungicides ROHM AND HAAS COMPANY (US) 1991-08-07 EP claimed