Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 7/20 | 0.49 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 9/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.46 |
| ▸ | HTR2B | P41595 | 5/20 | 0.45 |
| ▸ | HTR1A | P08908 | 2/20 | 0.45 |
| ▸ | DRD1 | P21728 | 1/20 | 0.45 |
| ▸ | HTR1D | P28221 | 1/20 | 0.45 |
| ▸ | HTR1B | P28222 | 1/20 | 0.45 |
| ▸ | HTR1E | P28566 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.45 |
| ▸ | HTR7 | P34969 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | HTR5A | P47898 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25381397 | 0.86 | CYP2A6 (0.50) | HTR2CCYP2A6HTR2AGPR84HTR2B | |
| SCHEMBL3478093 | 0.83 | HTR2A (0.68) | HTR2CCYP2A6HTR2AGPR84HTR2B | |
| SCHEMBL18509280 | 0.81 | GPR17 (0.55) | HTR2CCYP2A6HTR2AHTR2BHTR1A | |
| SCHEMBL3964357 | 0.81 | GPR84 (0.71) | HTR2CHTR2AGPR84HTR2BHTR1A | |
| SCHEMBL19799203 | 0.81 | HTR2C (0.73) | HTR2CHTR2AGPR84HTR2BHTR1A | |
| SCHEMBL29441748 | 0.81 | HTR2C (0.73) | HTR2CHTR2AGPR84HTR2BHTR1A | |
| SCHEMBL15767915 | 0.79 | HTR2A (0.73) | HTR2CHTR2AGPR84HTR2BHTR1A | |
| SCHEMBL4220443 | 0.79 | GPR84 (0.69) | HTR2CHTR2AGPR84HTR2BHTR1A | |
| SCHEMBL30936114 | 0.79 | HTR2A (0.68) | HTR2CHTR2AHTR2BHTR1ADRD1 | |
| SCHEMBL19216922 | 0.79 | CYP2A6 (0.54) | HTR2CCYP2A6HTR2AGPR84HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009006089-A2 | A2 ADENOSINE RECEPTOR AGONISTS | GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2009-01-08 | — | — | WO | disclosed |
| US-5830911-A | ANTIARTHRITIC AGENTS; ANTICARCINOGENIC AGENTS; ALZHEIMER'SDISEASE | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-11-03 | — | — | US | disclosed |