Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.33 |
| ▸ | P4HB | P07237 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.32 |
| ▸ | CTSD | P07339 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1177304 | 0.84 | MAOB (0.40) | CACNA1GMGLL | |
| SCHEMBL1177018 | 0.84 | CACNA1C (0.34) | IRAK4MGLLHDAC1HDAC8HDAC6 | |
| SCHEMBL18577187 | 0.84 | MAOB (0.40) | CACNA1GMGLL | |
| SCHEMBL1177522 | 0.84 | HDAC8 (0.41) | HDAC8CTSD | |
| SCHEMBL15133186 | 0.84 | HDAC8 (0.41) | HDAC8CTSD | |
| SCHEMBL8551693 | 0.84 | HDAC8 (0.41) | HDAC8CTSD | |
| SCHEMBL16767344 | 0.81 | GLA (0.47) | GAACACNA1GKMT2A | |
| SCHEMBL16767343 | 0.81 | GLA (0.47) | GAACACNA1GKMT2A | |
| SCHEMBL4229835 | 0.78 | MEN1 (0.49) | KMT2AHDAC6 | |
| SCHEMBL2477224 | 0.78 | HTR1D (0.46) | CAPN1GAACYP26A1CACNA1GKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090131420-A1 | Novel Heterocyclic Analogs of Biphenyl Ethers | ORCHID RESEARCH LABORATORIES, LTD. (IN) | 2009-05-21 | — | — | US | disclosed |
| US-20090131420-A1 | Novel Heterocyclic Analogs of Biphenyl Ethers | ORCHID RESEARCH LABORATORIES, LTD. (IN) | 2009-05-21 | — | — | US | disclosed |
| US-20090131420-A1 | Novel Heterocyclic Analogs of Biphenyl Ethers | ORCHID RESEARCH LABORATORIES, LTD. (IN) | 2009-05-21 | — | — | US | disclosed |
| US-20080267888-A1 | Heterocyclic Derivatives | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2008-10-30 | — | — | US | disclosed |
| US-20080267888-A1 | Heterocyclic Derivatives | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2008-10-30 | — | — | US | disclosed |
| US-20080267888-A1 | Heterocyclic Derivatives | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2008-10-30 | — | — | US | disclosed |
| WO-2007042878-A1 | NOVEL HETEROCYCLIC ANALOGS OF BIPHENYL ETHERS | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-04-19 | — | — | WO | disclosed |
| WO-2007042878-A1 | NOVEL HETEROCYCLIC ANALOGS OF BIPHENYL ETHERS | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-04-19 | — | — | WO | disclosed |
| WO-2006126074-A2 | HETEROCYCLIC DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2006-11-30 | — | — | WO | disclosed |
| WO-2006126074-A2 | HETEROCYCLIC DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2006-11-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080267888-A1 | Heterocyclic Derivatives | CYP11B2, MAPT, UGT1A1 | CAPN1 4554/4885GAA 515/4885CYP26A1 571/4885 |
| US-20090131420-A1 | Novel Heterocyclic Analogs of Biphenyl Ethers | UGT2B7, CYP4B1, CYP1B1 | CAPN1 4791/4885GAA 788/4885CYP26A1 54/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.