Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 7/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.39 |
| ▸ | OXTR | P30559 | 1/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3679453 | 1.00 | AVPR1A (0.41) | AVPR1ATMEM97SIGMAR1HRH3HSD11B1 | |
| SCHEMBL3682438 | 0.87 | AVPR1A (0.48) | AVPR1AHRH3HSD11B1AVPR2OXTR | |
| SCHEMBL3682178 | 0.82 | HSD11B1 (0.59) | HSD11B1NPY5R | |
| SCHEMBL3686552 | 0.79 | HSD11B1 (0.58) | HSD11B1NPY5R | |
| SCHEMBL4758939 | 0.75 | CTSB (0.41) | AVPR1AHRH3AVPR2 | |
| SCHEMBL4758938 | 0.75 | CTSB (0.41) | AVPR1AHRH3AVPR2 | |
| SCHEMBL3971621 | 0.74 | HSD11B1 (0.69) | HSD11B1 | |
| SCHEMBL3231283 | 0.73 | AVPR1A (0.54) | AVPR1AHRH3AVPR2OXTR | |
| SCHEMBL15963063 | 0.73 | AVPR1A (0.57) | AVPR1AHRH3AVPR2OXTR | |
| SCHEMBL5531225 | 0.72 | AVPR1A (0.53) | AVPR1ASIGMAR1HRH3AVPR2OXTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1773773-A4 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORP (US) | 2009-07-29 | — | — | EP | claimed |
| EP-1773773-A1 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | Incyte Corporation (US) | 2007-04-18 | — | — | EP | claimed |
| WO-2006002350-A1 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORPORATION (US) | 2006-01-05 | — | — | WO | claimed |