SCHEMBL4230862

SCHEMBL4230862

N[C@@H](CCC(=O)Oc1ccc(Cl)cc1)C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC1A5 Q15758 1/20 0.47
LTA4H P09960 4/20 0.45
KMT2A Q03164 3/20 0.44
TDP1 Q9NUW8 1/20 0.44
GRIK1 P39086 3/20 0.43
GRIK2 Q13002 2/20 0.43
GRIK3 Q13003 2/20 0.43
GRM8 O00222 1/20 0.43
GRM6 O15303 1/20 0.43
GRIN2D O15399 1/20 0.43
GRIN3B O60391 1/20 0.43
GSR P00390 1/20 0.43
CYP1A2 P05177 1/20 0.43
GRM5 P41594 1/20 0.43
GRIA1 P42261 1/20 0.43
GRIA2 P42262 1/20 0.43
GRIA3 P42263 1/20 0.43
SLC1A3 P43003 1/20 0.43
SLC1A2 P43004 1/20 0.43
SLC1A1 P43005 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1810781 0.85 LTA4H (0.55) LTA4HKMT2AGRIK1GRIK2GRIK3
SCHEMBL8064264 0.85 LTA4H (0.55) LTA4HKMT2AGRIK1GRIK2GRIK3
SCHEMBL2266753 0.84 GRM6 (0.46) LTA4HKMT2AGRIK1GRIK2GRIK3
SCHEMBL2266748 0.84 GRM6 (0.46) LTA4HKMT2AGRIK1GRIK2GRIK3
SCHEMBL27840105 0.84 GRIK1 (0.51) SLC1A5LTA4HKMT2AGRIK1GRIK2
SCHEMBL27840103 0.84 GRIK1 (0.51) SLC1A5LTA4HKMT2AGRIK1GRIK2
Hydrochloric Acid SCHEMBL14481953 0.83 GRIK1 (0.50) SLC1A5LTA4HKMT2AGRIK1GRIK2
Hydrochloric Acid SCHEMBL14481950 0.83 GRIK1 (0.50) SLC1A5LTA4HKMT2AGRIK1GRIK2
SCHEMBL18172341 0.80 KMT2A (0.50) LTA4HKMT2ATDP1ALDH1A1LMNA
SCHEMBL643983 0.79 KMT2A (0.63) KMT2ATDP1CYP1A2ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1874948-B1 Process for the production of y-glutamylcysteine NEWSOUTH INNOVATIONS PTY LTD (AU) 2013-03-20 EP disclosed
US-8236533-B2 Process for the production of γ-glutamylcysteine NEWSOUTH INNOVATIONS PTY LIMITED (AU) 2012-08-07 US disclosed
US-20090136993-A1 Process for the Production of Gamma-Glutamylcysteine NEWSOUTH INNOVATIONS PTY LIMITED 2009-05-28 US disclosed
EP-1874948-A1 PROCESS FOR THE PRODUCTION OF y-GLUTAMYLCYSTEINE Newsouth Innovations Pty Limited (AU) 2008-01-09 EP disclosed
WO-2006102722-A1 PROCESS FOR THE PRODUCTION OF Ϝ-GLUTAMYLCYSTEINE NEWSOUTH INNOVATIONS PTY LIMITED (AU) 2006-10-05 WO disclosed