Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5806103 | 0.88 | TAAR1 (0.55) | TAAR1ADRA2AADRA2BADRA2CPTGS1 | |
| SCHEMBL2032117 | 0.86 | TAAR1 (0.53) | TAAR1ADRA2AADRA2BADRA2CPTGS1 | |
| SCHEMBL9724105 | 0.84 | TAAR1 (0.52) | TAAR1ADRA2AADRA2BADRA2CPTGS1 | |
| SCHEMBL418868 | 0.78 | TAAR1 (0.54) | TAAR1ADRA2AADRA2BADRA2CPTGS1 | |
| SCHEMBL2030841 | 0.78 | TAAR1 (0.71) | TAAR1ADRA2AADRA2BADRA2CPTGS1 | |
| SCHEMBL10913191 | 0.77 | TAAR1 (0.44) | TAAR1ADRA2AADRA2BADRA2CPTGS1 | |
| SCHEMBL10917322 | 0.77 | TAAR1 (0.44) | TAAR1ADRA2AADRA2BADRA2CPTGS1 | |
| SCHEMBL5029219 | 0.77 | TAAR1 (0.46) | TAAR1ADRA2AADRA2BADRA2CSMN1; SMN2 | |
| SCHEMBL28505470 | 0.76 | TAAR1 (0.52) | TAAR1ADRA2AADRA2BADRA2CPTGS1 | |
| SCHEMBL4476863 | 0.75 | TAAR1 (0.50) | TAAR1ADRA2AADRA2BADRA2CPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108658989-B | Preparation method and application of cangrelor intermediate | 一禾(湖州)生物医药科技有限公司 | 2022-04-08 | — | — | CN | disclosed |
| US-20090320718-A1 | FLUOROSURFACTANTS | MERCK PATENT GESELLSCHAFT (DE) | 2009-12-31 | — | — | US | disclosed |
| EP-2035132-A2 | FLUOROSURFACTANTS | MERCK PATENT GmbH (DE) | 2009-03-18 | — | — | EP | disclosed |
| WO-2008003447-A2 | FLUOROSURFACTANTS | MERCK PATENT GMBH (DE) | 2008-01-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090320718-A1 | FLUOROSURFACTANTS | FPR3, Q6ZSR9, SGMS2 | TAAR1 2143/4885ADRA2A 1829/4885ADRA2B 2890/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.