Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | SSTR5 | P35346 | 6/20 | 0.41 |
| ▸ | KDM1A | O60341 | 7/20 | 0.40 |
| ▸ | RCOR1 | Q9UKL0 | 7/20 | 0.40 |
| ▸ | NSD2 | O96028 | 2/20 | 0.40 |
| ▸ | EHMT2 | Q96KQ7 | 9/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4381970 | 0.92 | SSTR5 (0.43) | SLC2A1SSTR5KDM1ARCOR1NSD2 | |
| SCHEMBL4237974 | 0.89 | SLC2A1 (0.43) | SLC2A1SSTR5KDM1ARCOR1NSD2 | |
| SCHEMBL3772048 | 0.82 | SSTR5 (0.54) | SSTR5KDM1ARCOR1NSD2EHMT2 | |
| SCHEMBL4232008 | 0.81 | SLC2A1 (0.44) | SLC2A1SSTR5KDM1ARCOR1NSD2 | |
| SCHEMBL4232216 | 0.78 | SSTR5 (0.47) | SSTR5KCNH2 | |
| SCHEMBL4232013 | 0.75 | SLC2A1 (0.42) | SLC2A1SSTR5NSD2EHMT2KCNH2 | |
| SCHEMBL3782357 | 0.73 | SSTR5 (0.57) | SSTR5KDM1ARCOR1NSD2EHMT2 | |
| SCHEMBL4381976 | 0.73 | SLC2A1 (0.44) | SLC2A1SSTR5KDM1ARCOR1NSD2 | |
| SCHEMBL3785396 | 0.71 | SSTR5 (0.58) | SSTR5KDM1ARCOR1NSD2EHMT2 | |
| SCHEMBL3767911 | 0.70 | EHMT2 (0.55) | SSTR5KDM1ARCOR1NSD2EHMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2001867-B1 | PYRIMIDINE, QUINAZOLINE, PTERIDINE AND TRIAZINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2009-07-01 | — | — | EP | disclosed |