Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
| ▸ | SSTR5 | P35346 | 4/20 | 0.38 |
| ▸ | EHMT2 | Q96KQ7 | 12/20 | 0.38 |
| ▸ | NSD2 | O96028 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4381979 | 0.93 | SLC2A1 (0.41) | SLC2A1SSTR5EHMT2NSD2 | |
| SCHEMBL4237980 | 0.90 | SLC2A1 (0.42) | SLC2A1SSTR5EHMT2NSD2 | |
| SCHEMBL4232008 | 0.78 | SLC2A1 (0.44) | SLC2A1SSTR5EHMT2NSD2KCNH2 | |
| Hydrochloric Acid SCHEMBL4235380 | 0.77 | SSTR5 (0.37) | SSTR5KCNH2 | |
| SCHEMBL4232006 | 0.75 | SLC2A1 (0.41) | SLC2A1SSTR5EHMT2NSD2KCNH2 | |
| Hydrochloric Acid SCHEMBL4373343 | 0.75 | SSTR5 (0.40) | SLC2A1SSTR5EHMT2KCNH2 | |
| SCHEMBL4237977 | 0.74 | SSTR5 (0.39) | SSTR5KCNH2 | |
| Hydrochloric Acid SCHEMBL4232638 | 0.73 | SSTR5 (0.40) | SLC2A1SSTR5KCNH2 | |
| Hydrochloric Acid SCHEMBL4231165 | 0.72 | SSTR5 (0.37) | SLC2A1SSTR5EHMT2NSD2KCNH2 | |
| SCHEMBL3772048 | 0.72 | SSTR5 (0.54) | SSTR5EHMT2NSD2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2001867-B1 | PYRIMIDINE, QUINAZOLINE, PTERIDINE AND TRIAZINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2009-07-01 | — | — | EP | disclosed |
| CN-101405284-A | Pyrimidine, quinazoline, pteridine and derivatives | HOFFMANN LA ROCHE (CH) | 2009-04-08 | — | — | CN | disclosed |