Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.44 |
| ▸ | SSTR5 | P35346 | 7/20 | 0.41 |
| ▸ | NSD2 | O96028 | 2/20 | 0.40 |
| ▸ | EHMT2 | Q96KQ7 | 5/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 3/20 | 0.36 |
| ▸ | RCOR1 | Q9UKL0 | 3/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 3/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4381976 | 0.91 | SLC2A1 (0.44) | SLC2A1SSTR5NSD2EHMT2KDM1A | |
| SCHEMBL4237976 | 0.88 | SLC2A1 (0.46) | SLC2A1SSTR5NSD2EHMT2KDM1A | |
| SCHEMBL4232220 | 0.81 | SSTR5 (0.46) | SSTR5KCNH2 | |
| SCHEMBL4232006 | 0.81 | SLC2A1 (0.41) | SLC2A1SSTR5NSD2EHMT2KCNH2 | |
| SCHEMBL3772048 | 0.78 | SSTR5 (0.54) | SSTR5NSD2EHMT2KCNH2KDM1A | |
| SCHEMBL4232013 | 0.78 | SLC2A1 (0.42) | SLC2A1SSTR5NSD2EHMT2KCNH2 | |
| Hydrochloric Acid SCHEMBL4235376 | 0.76 | SSTR5 (0.42) | SSTR5KCNH2 | |
| SCHEMBL4381970 | 0.73 | SSTR5 (0.43) | SLC2A1SSTR5NSD2EHMT2KDM1A | |
| SCHEMBL4237973 | 0.73 | SSTR5 (0.43) | SSTR5KCNH2 | |
| SCHEMBL4234952 | 0.72 | EHMT2 (0.51) | SSTR5NSD2EHMT2KCNH2KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2001867-B1 | PYRIMIDINE, QUINAZOLINE, PTERIDINE AND TRIAZINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2009-07-01 | — | — | EP | disclosed |