Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.52 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | ACLY | P53396 | 2/20 | 0.35 |
| ▸ | ACACA | Q13085 | 2/20 | 0.35 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.35 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.35 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | FNTA | P49354 | 1/20 | 0.34 |
| ▸ | FNTB | P49356 | 1/20 | 0.34 |
| ▸ | TYR | P14679 | 3/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.33 |
| ▸ | TOP2A | P11388 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29925026 | 1.00 | HSD11B1 (0.52) | HSD11B1HSD11B2ACHEPPARGACLY | |
| SCHEMBL4232635 | 1.00 | HSD11B1 (0.52) | HSD11B1HSD11B2ACHEPPARGACLY | |
| SCHEMBL24068241 | 0.89 | HSD11B1 (0.46) | HSD11B1HSD11B2ACHEPPARGPRKAG1 | |
| SCHEMBL4232501 | 0.89 | HSD11B1 (0.62) | HSD11B1HSD11B2ACHEACLYACACA | |
| SCHEMBL4232495 | 0.89 | HSD11B1 (0.62) | HSD11B1HSD11B2ACHEACLYACACA | |
| SCHEMBL24068231 | 0.83 | HSD11B1 (0.44) | HSD11B1HSD11B2ACHEPPARGACLY | |
| SCHEMBL30678790 | 0.83 | TYR (0.55) | HSD11B1HSD11B2TYRPSEN1PSEN2 | |
| SCHEMBL24068239 | 0.82 | HSD11B1 (0.43) | HSD11B1HSD11B2ACHEPPARGACLY | |
| SCHEMBL30678739 | 0.81 | TYR (0.57) | HSD11B1HSD11B2PRKAG1PRKAA2PRKAB1 | |
| SCHEMBL30678789 | 0.80 | TYR (0.60) | HSD11B1HSD11B2TYRPSEN1PSEN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2011517-A1 | Polynucleotide binding complexes comprising sterols and saponin | Nordic Vaccine Technology A/S (DK) | 2009-01-07 | — | — | EP | disclosed |
| EP-1377320-B1 | POLYNUCLEOTIDE BINDING COMPLEXES COMPRISING STEROLS AND SAPONINS | NORDIC VACCINE TECHNOLOGY AS (DK) | 2008-10-01 | — | — | EP | disclosed |