SCHEMBL24068241

SCHEMBL24068241

C[C@H](CC[C@H](O)C(C)(C)O)[C@H]1[C@@H](O)C[C@@]2(C)C3C[C@H](O)C4C(C)(C)[C@@H](O)CC[C@@]45C[C@@]35C[C@H](O)[C@]12C

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ HSD11B1 P28845 1/20 0.46
▸ HSD11B2 P80365 1/20 0.46
▸ ACHE P22303 1/20 0.39
▸ PRKAG1 P54619 1/20 0.35
▸ PRKAA2 P54646 1/20 0.35
▸ PRKAB1 Q9Y478 1/20 0.35
▸ FNTA P49354 1/20 0.34
▸ FNTB P49356 1/20 0.34
▸ PPARG P37231 1/20 0.33
▸ TOP2A P11388 1/20 0.31
▸ TOP2B Q02880 1/20 0.31
▸ NR1H4 Q96RI1 2/20 0.30
▸ CES2 O00748 1/20 0.30
▸ CRYAA P02489 1/20 0.30
▸ CRYAB P02511 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29925026 0.89 HSD11B1 (0.52) HSD11B1HSD11B2ACHEPRKAG1PRKAA2
SCHEMBL4232635 0.89 HSD11B1 (0.52) HSD11B1HSD11B2ACHEPRKAG1PRKAA2
SCHEMBL4232633 0.89 HSD11B1 (0.52) HSD11B1HSD11B2ACHEPRKAG1PRKAA2
SCHEMBL4232501 0.77 HSD11B1 (0.62) HSD11B1HSD11B2ACHEPRKAG1PRKAA2
SCHEMBL4232495 0.77 HSD11B1 (0.62) HSD11B1HSD11B2ACHEPRKAG1PRKAA2
SCHEMBL24068242 0.76 HSD11B1 (0.45) HSD11B1HSD11B2ACHEPRKAG1PRKAA2
SCHEMBL24068231 0.76 HSD11B1 (0.44) HSD11B1HSD11B2ACHEPPARG
SCHEMBL24068239 0.75 HSD11B1 (0.43) HSD11B1HSD11B2ACHEPPARG
SCHEMBL30678790 0.73 TYR (0.55) HSD11B1HSD11B2
SCHEMBL30678739 0.71 TYR (0.57) HSD11B1HSD11B2PRKAG1PRKAA2PRKAB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210369738-A1 PRODUCTION METHOD OF TELOMERASE ACTIVATORS AND TELOMERASE ACTIVATORS OBTAINED BY THIS METHOD IZMIR YUKSEK TEKNOLOJI ENSTITUSU (TR) 2021-12-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210369738-A1 PRODUCTION METHOD OF TELOMERASE ACTIVATORS AND TELOMERASE ACTIVATORS OBTAINED BY THIS METHOD TERT, TERB1, TERF2 HSD11B1 431/4885HSD11B2 972/4885ACHE 118/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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