Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.47 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.47 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11983843 | 0.92 | LTA4H (0.56) | LTA4HPTGS1PTGS2NR5A1KMT2A | |
| SCHEMBL28233564 | 0.89 | NR5A1 (0.62) | LTA4HNR5A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL13298116 | 0.87 | NR5A1 (0.66) | LTA4HNR5A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL9008240 | 0.87 | NR5A1 (0.66) | LTA4HNR5A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL17445865 | 0.87 | NR5A1 (0.66) | LTA4HNR5A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL3720136 | 0.85 | PTGS1 (0.53) | LTA4HPTGS1PTGS2SLC5A1SLC5A2 | |
| SCHEMBL4647002 | 0.85 | NR1I2 (0.46) | LTA4HNR5A1ALDH1A1GAACA12 | |
| SCHEMBL4229019 | 0.84 | LTA4H (0.53) | LTA4HSLC5A1SLC5A2KMT2AMEN1 | |
| SCHEMBL338731 | 0.84 | LTA4H (0.60) | LTA4HPTGS1PTGS2NR5A1SLC5A1 | |
| SCHEMBL1050330 | 0.84 | LTA4H (0.60) | LTA4HPTGS1PTGS2NR5A1SLC5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160060260-A1 | BROMODOMAIN INHIBITORS FOR TREATING DISEASE | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2016-03-03 | — | — | US | disclosed |
| US-20090209522-A1 | Heterocyclic Non-Peptide GNRH Antagonists | TAKEDA CAMBRIDGE LIMITED (GB) | 2009-08-20 | — | — | US | disclosed |
| EP-1896465-A1 | HETEROCYCLIC NON-PEPTIDE GNRH ANTAGONISTS | Takeda Cambridge Limited (GB) | 2008-03-12 | — | — | EP | disclosed |
| WO-2007000582-A1 | HETEROCYCLIC NON-PEPTIDE GNRH ANTAGONISTS | TAKEDA CAMBRIDGE LIMITED (GB) | 2007-01-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160060260-A1 | BROMODOMAIN INHIBITORS FOR TREATING DISEASE | BRDT, BRPF3, BRWD1 | LTA4H 3000/4885PTGS1 2477/4885PTGS2 3046/4885 |
| US-20090209522-A1 | Heterocyclic Non-Peptide GNRH Antagonists | GNRHR, GHRHR, FSHR | LTA4H 3809/4885PTGS1 2635/4885PTGS2 1948/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.