SCHEMBL423344

SCHEMBL423344

CCOC(=O)NCc1ccccc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPID Q08752 1/20 0.64
SMN1; SMN2 Q16637 4/20 0.59
TSHR P16473 2/20 0.59
MAPT P10636 3/20 0.59
ALOX15 P16050 1/20 0.58
GAA P10253 3/20 0.57
HDAC1 Q13547 2/20 0.56
NAMPT P43490 1/20 0.56
HDAC3 O15379 1/20 0.56
HDAC4 P56524 1/20 0.56
HDAC7 Q8WUI4 1/20 0.56
HDAC2 Q92769 1/20 0.56
HDAC10 Q969S8 1/20 0.56
HDAC11 Q96DB2 1/20 0.56
HDAC8 Q9BY41 1/20 0.56
HDAC6 Q9UBN7 1/20 0.56
HDAC9 Q9UKV0 1/20 0.56
HDAC5 Q9UQL6 1/20 0.56
NCOR2 Q9Y618 1/20 0.56
LMNA P02545 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL8878788 1.00 PPID (0.64) PPIDSMN1; SMN2TSHRMAPTALOX15
Methacrylic Acid SCHEMBL26097617 0.91 PPID (0.55) PPIDSMN1; SMN2TSHRMAPTALOX15
SCHEMBL10599026 0.90 TSHR (0.70) PPIDSMN1; SMN2TSHRMAPTALOX15
SCHEMBL7788580 0.87 TSHR (0.67) PPIDSMN1; SMN2TSHRALOX15GAA
SCHEMBL17342601 0.87 TSHR (0.55) PPIDSMN1; SMN2TSHRMAPTALOX15
SCHEMBL28540163 0.86 TSHR (0.61) PPIDSMN1; SMN2TSHRMAPTALOX15
SCHEMBL7422332 0.86 HDAC1 (0.55) PPIDMAPTHDAC1LMNAALDH1A1
SCHEMBL9136581 0.85 LMNA (0.69) SMN1; SMN2TSHRALOX15GAALMNA
SCHEMBL5705124 0.85 SMN1; SMN2 (0.64) PPIDSMN1; SMN2TSHRMAPTALOX15
SCHEMBL29194212 0.84 NPC1 (0.52) PPIDSMN1; SMN2TSHRMAPTALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 299 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110734073-B Preparation method of gel factor attapulgite assembled inorganic gel with double network structures 中国科学院兰州化学物理研究所 2021-11-19 CN claimed
CN-101528707-B 2- [ 1-phenyl-5-hydroxy or methoxy-4 alpha-methyl-hexahydrocyclopenta [ f ] indazol-5-yl ] ethylphenyl derivatives useful as glucocorticoid receptor ligands MERCK SHARP & DOHME 2012-11-07 CN claimed
CN-101528707-A 2- [ 1-phenyl-5-hydroxy or methoxy-4 alpha-methyl-hexahydrocyclopenta [ f ] indazol-5-yl ] ethylphenyl derivatives useful as glucocorticoid receptor ligands MERCK & CO INC (US) 2009-09-09 CN claimed
EP-1255728-B1 INTEGRATED PROCESS FOR THE PREPARATION OF AROMATIC ISOCYANATES AND PROCEDURES FOR EFFECTING THE RELATIVE INTERMEDIATE PHASES DOW GLOBAL TECHNOLOGIES INC (US) 2006-08-30 EP claimed
US-20030162995-A1 Integrated process for the preparation of aromatic isocyanates and procedures for effecting the relative intermediate phases DOW GLOBAL TECHNOLOGIES LLC 2003-08-28 US claimed
CN-1419538-A Integrated process for the preparation of aromatic isocyanates and procedures for effecting the relative intermediate phases ENICHEM SPA (IT) 2003-05-21 CN claimed
EP-1255728-A1 INTEGRATED PROCESS FOR THE PREPARATION OF AROMATIC ISOCYANATES AND PROCEDURES FOR EFFECTING THE RELATIVE INTERMEDIATE PHASES Enichem S.p.A. (IT) 2002-11-13 EP claimed
WO-2001056977-A1 INTEGRATED PROCESS FOR THE PREPARATION OF AROMATIC ISOCYANATES AND PROCEDURES FOR EFFECTING THE RELATIVE INTERMEDIATE PHASES ENICHEM S.P.A. (IT) 2001-08-09 WO claimed
US-5811402-A ANTICOAGULANTS, THROMBIN INHIBITORS ELI LILLY AND COMPANY (US) 1998-09-22 US claimed
EP-0796866-A1 Antithrombotic diamides ELI LILLY AND COMPANY (US) 1997-09-24 EP claimed
CN-1004353-B Process for preparing N-methyl carbamates 埃尼凯姆·辛泰希公司 1989-05-31 CN claimed
CN-85109417-A The preparation method of N-methyl carbamate class 1986-12-03 CN claimed
US-4384115-A Process for preparing tetrahydro-1,3-oxazin-2-ones THE DOW CHEMICAL COMPANY (US) 1983-05-17 US claimed
US-11905361-B2 Base proliferating agent, and base-reactive resin composition containing said base proliferating agent NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2024-02-20 US disclosed
CN-111918863-B Heterocyclic compounds 武田药品工业株式会社 2024-01-05 CN disclosed
CN-116323638-A Stapled peptides and methods thereof 弗格制药有限公司 2023-06-23 CN disclosed
EP-0016346-A1 Process for preparing urethanes BAYER AG (DE) 1980-10-01 EP disclosed
US-4122090-A Cyclic esters of 3,4-dihydroxy-thiophene-1,1-dioxide compounds and 3,4-dihydroxy-cyclopentadienone compounds BASF AKTIENGESELLSCHAFT (DE) 1978-10-24 US disclosed
US-4100351-A Method for preparing aromatic urethans ANIC, S.P.A. (IT) 1978-07-11 US disclosed
US-4100351-A Method for preparing aromatic urethans ANIC, S.P.A. (IT) 1978-07-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11905361-B2 Base proliferating agent, and base-reactive resin composition containing said base proliferating agent PCNA, MKI67, POLR1A PPID 3583/4885SMN1; SMN2 1393/4885TSHR 2835/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.