Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | PPID | Q08752 | 4/20 | 0.49 |
| ▸ | PPIB | P23284 | 1/20 | 0.49 |
| ▸ | PPIA | P62937 | 1/20 | 0.49 |
| ▸ | PPIG | Q13427 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10599026 | 0.94 | TSHR (0.70) | SMN1; SMN2TSHRLMNAGAAKDM4E | |
| SCHEMBL9136581 | 0.89 | LMNA (0.69) | SMN1; SMN2TSHRLMNAGAAKDM4E | |
| SCHEMBL5705119 | 0.86 | ALOX15 (0.56) | SMN1; SMN2TSHRLMNAGAAKDM4E | |
| SCHEMBL23528048 | 0.86 | SMN1; SMN2 (0.60) | SMN1; SMN2TSHRLMNAGAAKDM4E | |
| SCHEMBL31467556 | 0.86 | PPID (0.66) | SMN1; SMN2TSHRLMNAGAAKDM4E | |
| SCHEMBL12745804 | 0.86 | TSHR (0.60) | SMN1; SMN2TSHRLMNAGAAKDM4E | |
| SCHEMBL6333483 | 0.86 | SMN1; SMN2 (0.69) | SMN1; SMN2TSHRLMNAGAAKDM4E | |
| SCHEMBL14311316 | 0.86 | SMN1; SMN2 (0.60) | SMN1; SMN2TSHRLMNAGAAKDM4E | |
| SCHEMBL8148107 | 0.86 | TSHR (0.65) | SMN1; SMN2TSHRLMNAGAAKDM4E | |
| Benzene SCHEMBL8878788 | 0.85 | PPID (0.64) | SMN1; SMN2TSHRLMNAGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1255728-B1 | INTEGRATED PROCESS FOR THE PREPARATION OF AROMATIC ISOCYANATES AND PROCEDURES FOR EFFECTING THE RELATIVE INTERMEDIATE PHASES | DOW GLOBAL TECHNOLOGIES INC (US) | 2006-08-30 | — | — | EP | claimed |
| US-20030162995-A1 | Integrated process for the preparation of aromatic isocyanates and procedures for effecting the relative intermediate phases | DOW GLOBAL TECHNOLOGIES LLC | 2003-08-28 | — | — | US | claimed |
| EP-1255728-A1 | INTEGRATED PROCESS FOR THE PREPARATION OF AROMATIC ISOCYANATES AND PROCEDURES FOR EFFECTING THE RELATIVE INTERMEDIATE PHASES | Enichem S.p.A. (IT) | 2002-11-13 | — | — | EP | claimed |
| WO-2001056977-A1 | INTEGRATED PROCESS FOR THE PREPARATION OF AROMATIC ISOCYANATES AND PROCEDURES FOR EFFECTING THE RELATIVE INTERMEDIATE PHASES | ENICHEM S.P.A. (IT) | 2001-08-09 | — | — | WO | claimed |
| EP-1255728-B1 | INTEGRATED PROCESS FOR THE PREPARATION OF AROMATIC ISOCYANATES AND PROCEDURES FOR EFFECTING THE RELATIVE INTERMEDIATE PHASES | DOW GLOBAL TECHNOLOGIES INC (US) | 2006-08-30 | — | — | EP | disclosed |
| US-6992214-B2 | Integrated process for the preparation of aromatic isocyanates and procedures for effecting the relative intermediate phases | DOW GLOBAL TECHNOLOGIES INC. (US) | 2006-01-31 | — | — | US | disclosed |
| US-20030162995-A1 | Integrated process for the preparation of aromatic isocyanates and procedures for effecting the relative intermediate phases | DOW GLOBAL TECHNOLOGIES LLC | 2003-08-28 | — | — | US | disclosed |