Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4220573 | 0.95 | HPRT1 (0.42) | HPRT1PTGS2KDM4EHPGDCYP2C9 | |
| SCHEMBL4234828 | 0.94 | HPRT1 (0.40) | HPRT1PTGS2KDM4EHPGDCYP2C9 | |
| SCHEMBL4225812 | 0.92 | GRM5 (0.35) | HPRT1CYP2C9CYP2C19ALDH1A1GAA | |
| SCHEMBL4235496 | 0.91 | HPRT1 (0.38) | HPRT1PTGS2MAPTMEN1KMT2A | |
| SCHEMBL4221883 | 0.90 | PTGS1 (0.35) | PTGS2CYP2C9CYP2C19ALDH1A1MAPT | |
| SCHEMBL4218893 | 0.90 | NPC1 (0.39) | HPRT1BRD4PTGS2KDM4EALDH1A1 | |
| SCHEMBL4230146 | 0.89 | MAPT (0.36) | BRD4PTGS2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL4232197 | 0.89 | HPRT1 (0.34) | HPRT1PTGS2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL4226452 | 0.89 | MAOB (0.35) | HPRT1PTGS2KDM4EHPGDCYP2C9 | |
| SCHEMBL4225507 | 0.87 | HPRT1 (0.36) | HPRT1PTGS2KDM4EHPGDCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090082434-A1 | Dihydrobenzofuranyl Alkanamine Derivatives and Methods for Using Same | WYETH (US) | 2009-03-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090082434-A1 | Dihydrobenzofuranyl Alkanamine Derivatives and Methods for Using Same | HTR2C, HTR1A, HTR3A | HPRT1 2577/4885BRD4 2918/4885PTGS2 2246/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.