Hydrochloric Acid

Hydrochloric Acid

SCHEMBL4233990

CCC[n+]1cc[nH]c1CC.[Cl-]

nearest known ligand 0.00

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Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4233917 0.98
Iodide SCHEMBL17870265 0.96
SCHEMBL16700615 0.90
Hydrochloric Acid SCHEMBL4222866 0.88 MEN1 (0.31)
Hydrochloric Acid SCHEMBL4233269 0.86 SMN1; SMN2 (0.37)
SCHEMBL329039 0.86 HTT (0.32)
Hydrochloric Acid SCHEMBL4228899 0.86
Hydrochloric Acid SCHEMBL13274432 0.85 SMN1; SMN2 (0.40)
Hydrochloric Acid SCHEMBL4227985 0.85 SMN1; SMN2 (0.40)
Iodide SCHEMBL4267896 0.84 NPC1 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009102419-A2 ALUMINUM RECOVERY PROCESS THE UNIVERSITY OF ALABAMA (US) 2009-08-20 WO claimed
WO-2009131692-A1 SUBSTRATES FOR DELIVERY OF PHYSIOLOGICALLY ACTIVE AGENTS THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA (US) 2009-10-29 WO disclosed
WO-2009102419-A2 ALUMINUM RECOVERY PROCESS THE UNIVERSITY OF ALABAMA (US) 2009-08-20 WO disclosed