Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 17/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4012980 | 0.87 | P2RY12 (0.53) | P2RY12 | |
| SCHEMBL13768795 | 0.77 | P2RY12 (0.57) | P2RY12 | |
| SCHEMBL4049810 | 0.75 | P2RY12 (0.69) | P2RY12 | |
| SCHEMBL4013485 | 0.75 | P2RY12 (0.69) | P2RY12 | |
| SCHEMBL4013081 | 0.75 | P2RY12 (0.58) | P2RY12 | |
| SCHEMBL4012272 | 0.74 | P2RY12 (0.53) | P2RY12 | |
| SCHEMBL8426592 | 0.72 | ADORA3 (0.59) | P2RY12 | |
| SCHEMBL8426596 | 0.72 | ADORA3 (0.59) | P2RY12 | |
| SCHEMBL4011332 | 0.72 | P2RY12 (0.55) | P2RY12 | |
| SCHEMBL4011335 | 0.72 | P2RY12 (0.55) | P2RY12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2081433-A2 | TRIAZOLOPYRIMIDINE DERIVATIVES AS ADP P2Y12 RECEPTOR ANTAGONISTS | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-07-29 | — | — | EP | disclosed |
| WO-2008054795-A2 | TRIAZOLOPYRIMIDINE DERIVATIVES AS ADP P2Y12 RECEPTOR ANTAGONISTS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2008-05-08 | — | — | WO | disclosed |