Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.59 |
| ▸ | SLC29A1 | Q99808 | 3/20 | 0.58 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.58 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.54 |
| ▸ | PGK1 | P00558 | 1/20 | 0.53 |
| ▸ | PGK2 | P07205 | 1/20 | 0.53 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.53 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8426596 | 1.00 | ADORA3 (0.59) | ADORA3SLC29A1P2RY12ADORA2APGK1 | |
| SCHEMBL8423026 | 0.92 | P2RY12 (0.67) | ADORA3P2RY12ADORA2APGK1PGK2 | |
| SCHEMBL8423342 | 0.90 | ADORA3 (0.64) | ADORA3SLC29A1ADORA2APGK1PGK2 | |
| SCHEMBL8423332 | 0.90 | ADORA3 (0.64) | ADORA3SLC29A1ADORA2APGK1PGK2 | |
| SCHEMBL8426439 | 0.89 | ADORA3 (0.63) | ADORA3SLC29A1P2RY12ADORA2APGK1 | |
| SCHEMBL8426428 | 0.89 | ADORA3 (0.63) | ADORA3SLC29A1P2RY12ADORA2APGK1 | |
| SCHEMBL8426477 | 0.88 | P2RY12 (0.60) | ADORA3P2RY12ADORA2APGK1PGK2 | |
| SCHEMBL8780661 | 0.88 | P2RY12 (0.60) | ADORA3P2RY12ADORA2APGK1PGK2 | |
| SCHEMBL8422649 | 0.88 | ADORA3 (0.66) | ADORA3SLC29A1P2RY12ADORA2APGK1 | |
| SCHEMBL8422643 | 0.88 | ADORA3 (0.66) | ADORA3SLC29A1P2RY12ADORA2APGK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955447-A | ADMINISTERING AS ANTICOAGULANT; TREATING CARDIOVASCULAR DISORDERS | ASTRA PHARMACEUTICALS LIMITED (GB) | 1999-09-21 | — | — | US | disclosed |
| US-5721219-A | ANTICOAGULANTS | ASTRA PHARMACEUTICALS LTD. (GB) | 1998-02-24 | — | — | US | disclosed |
| EP-0683789-B1 | N-ALKYL-2-SUBSTITUTED ATP ANALOGUES | ASTRA PHARMA PROD (GB) | 1997-11-05 | — | — | EP | disclosed |