Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | CASP1 | P29466 | 3/20 | 0.56 |
| ▸ | CASP7 | P55210 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 8/20 | 0.56 |
| ▸ | MAOA | P21397 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20169884 | 0.86 | CYP3A4 (0.61) | CYP3A4CYP2D6CYP2C9CYP2C19MAPT | |
| SCHEMBL27491848 | 0.85 | KDM4E (0.66) | CYP3A4CYP2D6CYP2C9CYP2C19MAPT | |
| SCHEMBL4164670 | 0.84 | MAPT (0.60) | CYP3A4CYP2D6CYP2C9CYP2C19MAPT | |
| SCHEMBL25022832 | 0.81 | ABCG2 (0.73) | CYP3A4CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL31031167 | 0.79 | AR (0.58) | CYP3A4MAPTKDM4EMEN1CASP1 | |
| SCHEMBL17523229 | 0.79 | MAPT (0.61) | CYP3A4CYP2D6CYP2C9CYP2C19MAPT | |
| SCHEMBL2395500 | 0.78 | KDM4E (0.67) | CYP3A4CYP2D6CYP2C9CYP2C19MAPT | |
| SCHEMBL30667382 | 0.77 | ABCG2 (0.58) | CYP3A4MAPTKDM4EMEN1CASP1 | |
| SCHEMBL4160691 | 0.77 | MAPT (0.54) | CYP3A4MAPTKDM4EMEN1CASP1 | |
| SCHEMBL1180406 | 0.76 | ABCG2 (0.57) | CYP3A4CYP1A2CYP2D6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090182133-A1 | BENZOPYRANONE DERIVATIVES AND THEIR USE AS ANTI-VIRAL AGENTS | SINGAPORE POLYTECHNIC | 2009-07-16 | — | — | US | disclosed |
| EP-1968569-A4 | BENZOPYRANONE DERIVATIVES AND THEIR USE AS ANTI-CORONAVIRAL AGENTS | SINGAPORE POLYTECHNIC (SG) | 2008-12-17 | — | — | EP | disclosed |
| EP-1968569-A1 | BENZOPYRANONE DERIVATIVES AND THEIR USE AS ANTI-CORONAVIRAL AGENTS | Singapore Polytechnic (SG) | 2008-09-17 | — | — | EP | disclosed |
| WO-2007075145-A1 | BENZOPYRANONE DERIVATIVES AND THEIR USE AS ANTI-CORONAVIRAL AGENTS | SINGAPORE POLYTECHNIC (SG) | 2007-07-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090182133-A1 | BENZOPYRANONE DERIVATIVES AND THEIR USE AS ANTI-VIRAL AGENTS | SARS1, MAVS, ACE2 | CYP3A4 222/4885CYP1A2 819/4885CYP2D6 588/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.