SCHEMBL42357

SCHEMBL42357

CC(C)(Cl)c1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.58
MAPK1 P28482 1/20 0.50
ALDH1A1 P00352 3/20 0.46
CYP1A2 P05177 1/20 0.46
TAAR1 Q96RJ0 1/20 0.46
ALOX15 P16050 1/20 0.46
ESR1 P03372 2/20 0.44
ESR2 Q92731 2/20 0.44
CYP3A4 P08684 1/20 0.44
KCNN4 O15554 3/20 0.43
MAPT P10636 1/20 0.42
KMT2A Q03164 1/20 0.42
CYP2C19 P33261 1/20 0.41
HIF1A Q16665 1/20 0.41
CYP2B6 P20813 1/20 0.39
HDAC3 O15379 1/20 0.39
HDAC4 P56524 1/20 0.39
HDAC1 Q13547 1/20 0.39
HDAC7 Q8WUI4 1/20 0.39
HDAC2 Q92769 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7046771 0.97 TSHR (0.55) TSHRMAPK1ALDH1A1CYP1A2TAAR1
Hydrogen Peroxide SCHEMBL9456436 0.97 TSHR (0.55) TSHRMAPK1ALDH1A1CYP1A2TAAR1
SCHEMBL13705008 0.84 KIF11 (0.52) TSHRMAPK1ALDH1A1CYP1A2TAAR1
Tert-Amylbenzene SCHEMBL28391499 0.83 TAAR1 (0.50) TSHRMAPK1ALDH1A1CYP1A2TAAR1
SCHEMBL45199 0.83 MEN1 (0.41) TSHRMAPK1ALDH1A1ALOX15ESR1
SCHEMBL2743453 0.81 TSHR (0.58) TSHRMAPK1ALDH1A1CYP1A2TAAR1
SCHEMBL686644 0.81 TSHR (0.58) TSHRMAPK1ALDH1A1CYP1A2TAAR1
SCHEMBL15415825 0.80 TSHR (0.50) TSHRMAPK1ALDH1A1CYP1A2TAAR1
SCHEMBL11405800 0.80 TSHR (0.39) TSHRMAPK1ALDH1A1CYP1A2ALOX15
SCHEMBL2701561 0.79 TSHR (0.55) TSHRMAPK1ALDH1A1CYP1A2TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1341 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120118222-A Method for continuously photochemically synthesizing telechelic polymer by utilizing micro-reaction device and application thereof 北京石油化工学院 2025-06-10 CN claimed
CN-120004749-A Phosphorus binding agent, preparation thereof and application thereof in medicaments for treating hyperphosphatemia 泰州市中医院 2025-05-16 CN claimed
CN-117887093-B Macromolecular branching agent, star-branched polymer and preparation method and application thereof 浙江信汇新材料股份有限公司 2025-04-29 CN claimed
CN-119735767-A Method for preparing polyisobutene and block copolymer thereof by Fe system coinitiator 北京石油化工学院 2025-04-01 CN claimed
CN-119708491-A Polydisulfide polymer material containing hydroxy ester group and preparation method thereof 衢州化工新材料创新研究院 2025-03-28 CN claimed
CN-119661754-A Synthesis method of narrow-distribution poly-p-acetoxyl styrene and copolymer thereof 青岛科技大学 2025-03-21 CN claimed
CN-119371582-A Polybutadiene composite rubber and preparation method thereof, rubber composition and application thereof 中国石油化工股份有限公司 2025-01-28 CN claimed
CN-119119482-A Polymer network hybrid material containing disulfide bond and ether bond, and preparation method and application thereof 常州汉韦聚合物有限公司 2024-12-13 CN claimed
EP-4406982-A2 PRODUCTION OF ISOBUTYLENE HOMO- OR COPOLYMER DERIVATIVES BASF SE (DE) 2024-07-31 EP claimed
CN-118271615-A Sulfur-containing polymer-based optical material with high light transmittance, high refraction and low dispersion and preparation method thereof 常州汉韦聚合物有限公司 2024-07-02 CN claimed
WO-1991011468-A1 NEW THERMOPLASTIC ELASTOMERS THE UNIVERSITY OF AKRON (US) 1991-08-08 WO claimed
US-5037994-A Regioselective nitration of diphenyl compounds AMOCO CORPORATION (US) 1991-08-06 US claimed
US-4946899-A CARBOCATIONIC POLYMERIZATION INVOLVING HOMOPOLYMERIZATION OF ELASTOMER FOLLOWED BY COPOLYMERIZATION TO ADD GLASSY SEGMENTS; FORMING LIVING POLYMERS WITH A METAL HALIDE, PROMOTER AND SOLVENT MIXTURE THE UNIVERSITY OF AKRON (US) 1990-08-07 US claimed
EP-0341012-A2 Uniform molecular weight polymers EDISON POLYMER INNOVATION CORPORATION ( EPIC) (US) 1989-11-08 EP claimed
EP-0281929-A1 Process for the preparation of olefines starting from tertiary alkyl halides BASF Aktiengesellschaft (DE) 1988-09-14 EP claimed
EP-0088218-B1 PREPARATION OF TERTIARY ALKYL ISOCYANATES AMERICAN CYANAMID COMPANY (US) 1985-05-08 EP claimed
EP-0088218-A1 Preparation of tertiary alkyl isocyanates AMERICAN CYANAMID COMPANY (US) 1983-09-14 EP claimed
US-4399074-A FROM THE HALIDE, CATALYST COMPLEX OF ZINC SALT, PYRIDINE AND ALKALI METAL CYANATE AMERICAN CYANAMID COMPANY (US) 1983-08-16 US claimed
US-4399073-A FROM THE HALIDE AND ALKALI METAL CYANATE, WATER AMERICAN CYANAMID COMPANY (US) 1983-08-16 US claimed
US-3953530-A Process for making o- and p-chlorophenols S. A. TEXACO BELGIUM N.V. (BE) 1976-04-27 US claimed