SCHEMBL45199

SCHEMBL45199

CC(C)(Cl)c1ccc(C(C)(C)Cl)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
TSHR P16473 6/20 0.40
ESR1 P03372 6/20 0.38
ESR2 Q92731 5/20 0.38
HPGD P15428 2/20 0.38
HSD17B10 Q99714 2/20 0.38
CYP3A4 P08684 2/20 0.38
LMNA P02545 1/20 0.38
TYR P14679 1/20 0.38
AR P10275 1/20 0.38
SLC6A2 P23975 1/20 0.38
SLC6A4 P31645 1/20 0.38
HTR6 P50406 1/20 0.38
ESRRG P62508 1/20 0.38
SLC6A3 Q01959 1/20 0.38
PDE2A O00408 1/20 0.36
MAPK1 P28482 1/20 0.35
HIF1A Q16665 1/20 0.35
ALDH1A1 P00352 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13704994 0.90 TSHR (0.55) TSHRHPGDHSD17B10LMNATYR
SCHEMBL9785061 0.90 KIF11 (0.44) MEN1KMT2ATSHRESR1ESR2
SCHEMBL677101 0.87 MEN1 (0.59) MEN1KMT2ATSHRHPGDLMNA
SCHEMBL10576971 0.87 TSHR (0.60) MEN1KMT2ATSHRHPGDLMNA
SCHEMBL23824228 0.85 TSHR (0.57) MEN1KMT2ATSHRHPGDALDH1A1
SCHEMBL13704982 0.85 IDO1 (0.41) MEN1KMT2ATSHRESR1ESR2
SCHEMBL11663437 0.85 ACHE (0.41) MEN1KMT2ACYP3A4LMNAMAPK1
SCHEMBL678140 0.85 ALDH1A1 (0.48) MEN1KMT2ATSHRHPGDHSD17B10
SCHEMBL7389 0.85 APP (0.44) MEN1KMT2ATSHRESR1ESR2
SCHEMBL678367 0.85 ESR1 (0.62) MEN1KMT2ATSHRESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 874 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118702951-A Preparation method of film for photovoltaic capacitor 浙江南洋华诚科技股份有限公司 2024-09-27 CN claimed
CN-117624688-A Preparation method of film for photovoltaic capacitor 浙江南洋华诚科技有限公司 2024-03-01 CN claimed
CN-112608402-B Styrene block copolymer and preparation method thereof 北京化工大学 2022-02-11 CN claimed
CN-109694454-A Preparation method of block copolymer and monovinylarene-isomonoolefin-monovinylarene block copolymer 中国石油化工股份有限公司 2019-04-30 CN claimed
CN-109694453-A Preparation method of block copolymer and monovinylarene-isomonoolefin-monovinylarene block copolymer 中国石油化工股份有限公司 2019-04-30 CN claimed
CN-108314820-A Stretched film and preparation method thereof 青岛软盛塑业有限公司 2018-07-24 CN claimed
CN-106146705-B Preparation method of halogenated polymer 中国石油化工股份有限公司 2018-06-15 CN claimed
CN-106146707-A Preparation method of halogenated polymer 中国石油化工股份有限公司 2016-11-23 CN claimed
CN-106146710-A Cationic polymerization method 中国石油化工股份有限公司 2016-11-23 CN claimed
CN-106146711-A Cationic polymerization method 中国石油化工股份有限公司 2016-11-23 CN claimed
US-RE34640-E Polymerizing isobutylene, adding monomer to make block polymer; metal halide, initiator and electron pair doner solvent UNIVERSITY OF AKRON (US) 1994-06-14 US claimed
EP-0341012-B1 UNIFORM MOLECULAR WEIGHT POLYMERS EDISON POLYMER INNOVATION CORPORATION ( EPIC) (US) 1992-12-30 EP claimed
WO-1991011468-A1 NEW THERMOPLASTIC ELASTOMERS THE UNIVERSITY OF AKRON (US) 1991-08-08 WO claimed
US-4946899-A CARBOCATIONIC POLYMERIZATION INVOLVING HOMOPOLYMERIZATION OF ELASTOMER FOLLOWED BY COPOLYMERIZATION TO ADD GLASSY SEGMENTS; FORMING LIVING POLYMERS WITH A METAL HALIDE, PROMOTER AND SOLVENT MIXTURE THE UNIVERSITY OF AKRON (US) 1990-08-07 US claimed
US-4891441-A Process for the preparation of polymeric tertiary aralkyl isocyanates from 1,3- or 1,4-bis(1-chloro-1-methylethyl)benzene AMERICAN CYANAMID (US) 1990-01-02 US claimed
EP-0341012-A2 Uniform molecular weight polymers EDISON POLYMER INNOVATION CORPORATION ( EPIC) (US) 1989-11-08 EP claimed
EP-0164521-B1 PROCESS FOR THE PREPARATION OF POLYMERIC TERTIARY ARALKYL ISOCYANATES FROM 1,3- OR 1,4-BIS(1-CHLORO-1-METHYLETHYL)BENZENE AMERICAN CYANAMID COMPANY (US) 1988-10-19 EP claimed
EP-0164521-A1 Process for the preparation of polymeric tertiary aralkyl isocyanates from 1,3- or 1,4-bis(1-chloro-1-methylethyl)benzene AMERICAN CYANAMID COMPANY (US) 1985-12-18 EP claimed
EP-0083685-B1 MANUFACTURE OF DIISOCYANATES AMERICAN CYANAMID COMPANY (US) 1985-03-06 EP claimed
US-4376841-A Copolymerization of unsaturated polyester resins AKZONA INCORPORATED (US) 1983-03-15 US claimed