⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11030516 | 0.96 | — | — | |
| Hydrochloric Acid SCHEMBL28140997 | 0.96 | — | — | |
| SCHEMBL4922033 | 0.77 | — | — | |
| SCHEMBL861862 | 0.77 | — | — | |
| Trifluoroacetic Acid SCHEMBL29021584 | 0.77 | ALDH1A1 (0.36) | — | |
| SCHEMBL42331 | 0.76 | — | — | |
| SCHEMBL10865868 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL622579 | 0.74 | — | — | |
| SCHEMBL241832 | 0.72 | CA1 (0.35) | — | |
| SCHEMBL604854 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1304 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112739701-B | Fused pyrimidine skeleton sulfonamide derivative with inhibition effect of epidermal growth factor receptor mutation | 韩美药品株式会社 | 2024-02-13 | — | — | CN | claimed |
| CN-111386266-B | Pyrimidine derivatives having cancer cell growth inhibiting effect and pharmaceutical compositions containing the same | 昂科比克斯有限公司 | 2023-08-04 | — | — | CN | claimed |
| EP-2694505-B1 | HSP90 INHIBITORS | SLOAN KETTERING INST CANCER RES (US) | 2022-04-27 | — | — | EP | claimed |
| US-20210198203-A1 | COMPOUNDS, COMPOSITIONS AND METHODS | CYTOKINETICS, INCORPORATED | 2021-07-01 | — | — | US | claimed |
| EP-3458455-B1 | NOVEL PYRAZINE COMPOUNDS WITH OXYGEN, SULFUR AND NITROGEN LINKER FOR THE TREATMENT OF INFECTIOUS DISEASES | HOFFMANN LA ROCHE (CH) | 2021-06-16 | — | — | EP | claimed |
| US-10604527-B2 | Pyrazine compounds for the treatment of hepatitis B infection | HOFFMANN-LA ROCHE INC. (US) | 2020-03-31 | — | — | US | claimed |
| WO-2020060268-A1 | NOVEL SULFONAMIDE DERIVATIVE WITH FUSED PYRIMIDINE SKELETON, HAVING EPIDERMAL GROWTH FACTOR RECEPTOR MUTATION INHIBITORY EFFECT | 한미약품 주식회사 | 2020-03-26 | — | — | WO | claimed |
| US-20190352267-A1 | COMPOUNDS, COMPOSITIONS AND METHODS | CYTOKINETICS, INCORPORATED | 2019-11-21 | — | — | US | claimed |
| US-20190185476-A1 | NOVEL PYRAZINE COMPOUNDS WITH OXYGEN SULFUR AND NITROGEN LINKER FOR THE TREATMENT OF INFECTIOUS DISEASES | HOFFMANN-LA ROCHE INC. (US) | 2019-06-20 | — | — | US | claimed |
| EP-3458455-A1 | NOVEL PYRAZINE COMPOUNDS WITH OXYGEN, SULFUR AND NITROGEN LINKER FOR THE TREATMENT OF INFECTIOUS DISEASES | H. Hoffnabb-La Roche Ag (CH) | 2019-03-27 | — | — | EP | claimed |
| WO-1993021178-A1 | INDOLE DERIVATIVES AS 5-HT1-LIKE AGONISTS | PFIZER LIMITED (GB) | 1993-10-28 | — | — | WO | claimed |
| EP-0519235-A1 | Preparation of alkanesulfonamides | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1992-12-23 | — | — | EP | claimed |
| US-5166431-A | Reacting ammonia, methylamine, or dimethylamine with alkanesulfonyl halide in cyclic saturated ether; removal of amine salt by-product | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1992-11-24 | — | — | US | claimed |
| EP-0495594-A1 | Sulphonamide derivatives | ZENECA LIMITED (GB) | 1992-07-22 | — | — | EP | claimed |
| EP-0167107-B1 | PROCESS FOR THE MANUFACTURE OF AQUEOUS, FLUID PREPARATIONS OF REACTIVE DYES WITH A LOW SALT CONTENT | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-05-08 | — | — | EP | claimed |
| US-4981864-A | ANTICOAGULANTS | BOEHRINGER MANNEHIM GMBH (DE) | 1991-01-01 | — | — | US | claimed |
| CN-85105802-B | Process for preparing low-salt aqueous preparations of fibre-reactive dyes | 赫司特公司 | 1988-07-20 | — | — | CN | claimed |
| EP-0074894-B1 | PROCESS FOR THE PURIFICATION OF A GASEOUS MIXTURE CONTAINING UNDESIRABLE GASEOUS COMPOUNDS | COMPAGNIE FRANCAISE DE RAFFINAGE Société anonyme dite: (FR) | 1985-01-02 | — | — | EP | claimed |
| EP-0094239-A2 | 1,3-Dioxan-5-ylalkenoic acids | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1983-11-16 | — | — | EP | claimed |
| US-4170547-A | SOLVENT EXTRACTION | COMPAGNIE FRANCAISE DE RAFFINAGE (FR) | 1979-10-09 | — | — | US | claimed |