SCHEMBL423604

SCHEMBL423604

O=C1C=C(S(=O)(=O)O)c2ccccc2C1=O.[NaH]

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 9/20 0.61
KDM4E B2RXH2 2/20 0.53
MAPT P10636 2/20 0.53
ALDH1A1 P00352 1/20 0.53
CYP3A4 P08684 1/20 0.53
HPGD P15428 1/20 0.53
MAPK1 P28482 1/20 0.53
PTPN22 Q9Y2R2 1/20 0.53
PTPRC P08575 3/20 0.48
NSD2 O96028 1/20 0.48
HKDC1 Q2TB90 1/20 0.48
CDC25B P30305 2/20 0.46
PTPRF P10586 1/20 0.46
MALT1 Q9UDY8 2/20 0.44
POLB P06746 1/20 0.43
RECQL P46063 1/20 0.43
ATM Q13315 1/20 0.43
DNMT1 P26358 1/20 0.43
RHOA P61586 1/20 0.43
MEN1 O00255 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29397292 0.98 PTPN1 (0.63) PTPN1KDM4EMAPTALDH1A1CYP3A4
SCHEMBL366178 0.98 PTPN1 (0.63) PTPN1KDM4EMAPTALDH1A1CYP3A4
SCHEMBL423605 0.96 PTPN1 (0.61) PTPN1KDM4EMAPTALDH1A1CYP3A4
Potassium SCHEMBL4798700 0.96 PTPN1 (0.61) PTPN1KDM4EMAPTALDH1A1CYP3A4
SCHEMBL4181599 0.96 PTPN1 (0.61) PTPN1KDM4EMAPTALDH1A1CYP3A4
Ammonia Solution, Strong SCHEMBL5163658 0.96 PTPN1 (0.61) PTPN1KDM4EMAPTALDH1A1CYP3A4
Nitrogen SCHEMBL27516868 0.94 PTPN1 (0.59) PTPN1KDM4EMAPTALDH1A1CYP3A4
Nitrogen SCHEMBL27833936 0.92 PTPN1 (0.58) PTPN1KDM4EMAPTALDH1A1CYP3A4
SCHEMBL7528393 0.86 PTPN1 (0.51) PTPN1KDM4EMAPTALDH1A1CYP3A4
SCHEMBL465090 0.84 MAPT (0.48) PTPN1KDM4EMAPTALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12625127-B2 Field test for determining concentration of emulsifiers in drilling fluids using dyes HALLIBURTON ENERGY SERVICES, INC. (US) 2026-05-12 US claimed
US-20240329029-A1 FIELD TEST FOR DETERMINING CONCENTRATION OF EMULSIFIERS IN DRILLING FLUIDS USING DYES HALLIBURTON ENERGY SERVICES, INC. (US) 2024-10-03 US claimed
CN-115504866-B Preparation method and application of 4-methoxy-2-naphthol 阜阳欣奕华制药科技有限公司 2023-09-26 CN claimed
CN-116454419-A Self-deoxidizing electrolyte additive for zinc metal battery, electrolyte and zinc metal battery 天津大学 2023-07-18 CN claimed
CN-113504212-B Method and device for detecting organic amine in liquid phase, readable storage medium and equipment 中国科学院上海微系统与信息技术研究所 2022-11-08 CN claimed
CN-113504212-A Method and device for detecting organic amine in liquid phase, readable storage medium and equipment 中国科学院上海微系统与信息技术研究所 2021-10-15 CN claimed
CN-111349953-A Environment-friendly carrier-free water-based sulfate zinc plating additive 武汉奥邦表面技术有限公司 2020-06-30 CN claimed
WO-2010042500-A2 HEAT SHOCK PROTEIN 90 INHIBITORS, METHODS OF PREPARING SAME, AND METHODS FOR THEIR USE EMORY UNIVERSITY (US) 2010-04-15 WO claimed
EP-1754514-A1 Agent and method for colouring keratin fibres Wella Aktiengesellschaft (DE) 2007-02-21 EP claimed
US-20070000073-A1 Agent and method for colouring keratin fibres PROCTER & GAMBLE COMPANY, THE 2007-01-04 US claimed
US-7070625-B2 Agent and method for coloring keratin fibers containing 2-benzothiazolinone-hydrazone and quinone derivatives WELLA AG (DE) 2006-07-04 US claimed
US-20040060124-A1 Agent and method for coloring keratin fibers containing 2-benzothiazolinone-hydrazone and quinone derivatives HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) 2004-04-01 US claimed
CN-1106388-C Method and composition for regenerating aminal compounds QUAKER CHEM CORP (US) 2003-04-23 CN claimed
CN-1261859-A Method and composition for regeneration of an aminal compound QUAKER CHEM CORP (US) 2000-08-02 CN claimed
US-5324815-A Polyaniline NITTO DENKO CORPORATION (JP) 1994-06-28 US claimed
US-12625127-B2 Field test for determining concentration of emulsifiers in drilling fluids using dyes HALLIBURTON ENERGY SERVICES, INC. (US) 2026-05-12 US disclosed
CN-121499815-A Urine microalbumin detection reagent, urine microalbumin semi-quantitative detection test paper and preparation method thereof 桂林中辉科技发展有限公司 2026-02-10 CN disclosed
US-4204870-A METALLIZED DYES EASTMAN KODAK COMPANY (US) 1980-05-27 US disclosed
US-4199553-A HYDROGEN SULFIDE AND HYDROGEN CYANIDE KAWADA TATSUYA 1980-04-22 US disclosed
US-3937795-A OXIDATION CATALYSTS, CHELATE COMPOUNDS, QUINONES AND HYDROQUINONES, ABSORPTION 3937795 3937795 NEW WORLD BUSINESS CORPORATION, A CA CORP. 1976-02-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040060124-A1 Agent and method for coloring keratin fibers containing 2-benzothiazolinone-hydrazone and quinone derivatives KRT18, NDUFA1, NDUFA2 PTPN1 2186/4885KDM4E 2619/4885MAPT 1723/4885
US-20070000073-A1 Agent and method for colouring keratin fibres KRT18, CDC73, OAT PTPN1 2020/4885KDM4E 1848/4885MAPT 1013/4885
US-12625127-B2 Field test for determining concentration of emulsifiers in drilling fluids using dyes LIPA, TES, CETP PTPN1 4569/4885KDM4E 3828/4885MAPT 1479/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.