NDUFA1 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
Auraptene (SCHEMBL2535029)	1.00	5/20
Auraptene (SCHEMBL2535034)	1.00	5/20
SCHEMBL8491443	0.56	4/20
SCHEMBL8489900	0.52	4/20
SCHEMBL8489907	0.52	4/20
SCHEMBL8489902	0.51	4/20
SCHEMBL8489908	0.51	4/20
SCHEMBL8491154	0.51	4/20
SCHEMBL8491160	0.51	4/20
SCHEMBL8491619	0.50	4/20
SCHEMBL8491624	0.50	4/20
SCHEMBL8491634	0.50	4/20
7-Prenyloxycoumarin (SCHEMBL4898255)	0.79	3/20
SCHEMBL712741	0.57	3/20
Geiparvarin (SCHEMBL2532495)	0.56	3/20
SCHEMBL6267768	0.55	3/20
SCHEMBL1095981	0.55	3/20
SCHEMBL4293165	0.55	3/20
SCHEMBL8490928	0.53	3/20
SCHEMBL8490937	0.53	3/20

Clinical trials — most relevant to NDUFA1 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Phase III Trial of Coenzyme Q10 in Mitochondrial Disease	PHASE3	COMPLETED
Coenzyme Q10 as a Symptomatic Treatment in Parkinson's Disease	PHASE3	COMPLETED
Effect of Montelukast Versus Co Enzyme in Sepsis	PHASE2/PHASE3	COMPLETED
Mitochondrial Dysfunction in the Pathophysiology and Treatment of Bipolar Disorder	PHASE2	WITHDRAWN
A Study of Bezafibrate in Mitochondrial Myopathy	PHASE2	COMPLETED
Trial of Nicotinamide Riboside and Co-enzyme Q10 in Chronic Kidney Disease	PHASE2	COMPLETED
A Study to Evaluate Vitamin B3 Derivative to Treat Mitochondrial Myopathy	PHASE2	ACTIVE_NOT_RECRUITING
Parkinson's Disease Treatment With Coenzyme Q10	PHASE2	COMPLETED
Does Clinical Treatment of Mitochondrial Dysfunction Impact Autism Spectrum Disorder (ASD)?	PHASE1	UNKNOWN
Genomic Profiling of Mitochondrial Disease - Imaging Analysis for Precise Mitochondrial Medicine	nan	COMPLETED
The Natural History of Mitochondrial Diseases	nan	RECRUITING
North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)	nan	RECRUITING
Tissue Sample Study for Mitochondrial Disorders	nan	ENROLLING_BY_INVITATION
Nicotinamide Riboside and Mitochondrial Biogenesis	nan	COMPLETED
Natural History in Primary Mitochondrial Myopathies	nan	RECRUITING
Effect of Subtle Energy Transmission and Tao Calligraphy Mindfulness Practice on Mitochondrial DNA in Peripheral Blood Leukocytes	nan	NOT_YET_RECRUITING
Identification of New Candidate Genes in Patients With Mitochondrial Disease by High Resolution Chromosome Analysis on DNA Chip	nan	COMPLETED
Nicotinamide Riboside in Ulcerative Colitis	nan	RECRUITING
MITOMICS : a Multi-OMICS Approach for the Diagnosis of Mitochondrial Diseases	nan	RECRUITING
A Study Into the Underlying Biochemical Pathways Involved in Parkinson's Disease, Such as Mitochondrial (Cellular Powerhouse) Dysfunction	nan	COMPLETED
GDF-15 as a Biomarker for Mitochondrial Disease	nan	COMPLETED
Identification of Large-Scale Mutations of POLG Gene by QMPSF in Patients With Mitochondrial DNA Instability.	nan	UNKNOWN
Diagnostic Odyssey Survey 2	nan	COMPLETED
Coenzyme Q10 Plus NADH Supplementation in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis	nan	COMPLETED
Abnormalities in the Effects of Insulin and Exercise on Glucose- and Lipid Metabolism in Obesity and Type 2 Diabetes	nan	COMPLETED
Assessment of Follicular Fluid Level of Coenzyme Q10 in Women Undergoing ICSI	nan	UNKNOWN
Evaluation of Impact of Disease and Visual Disability on Quality of Life and Loss of Independence of Patients Living in France With Leber's Hereditary Optic Neuropathy (LHON) Through Qualitative and Quantitative Data Collection	nan	COMPLETED
Survey on Supplement Use in Mitochondrial Disease	nan	COMPLETED
Gastrointestinal Dysfunction in Children Affected With Mitochondrial Disorders	nan	COMPLETED
Exercise-mediated Rescue of Mitochondrial Dysfunctions Driving Insulin Resistance	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a NDUFA1 binder may also engage these)

Protein	Name	Similarity
Q7JGX4	—	1.000	Q7JGX4 →
Q8SPF0	—	1.000	Q8SPF0 →
Q8SPS2	—	1.000	Q8SPS2 →
Q9WU08	—	1.000	Q9WU08 →
Q02377	—	1.000	Q02377 →
O35683	—	1.000	O35683 →
Q9C0X5	—	0.990	Q9C0X5 →
Q6BY05	—	0.990	Q6BY05 →
Q54ND0	—	0.989	Q54ND0 →
B9WK46	—	0.989	B9WK46 →
C4YTL7	—	0.988	C4YTL7 →
Q0MQD4	—	0.987	Q0MQD4 →
Q0MQD5	—	0.987	Q0MQD5 →
O94705	—	0.987	O94705 →
Q9W380	—	0.987	Q9W380 →
Q86IZ2	—	0.987	Q86IZ2 →
G2TRJ9	—	0.986	G2TRJ9 →
Q9CQ91	—	0.986	Q9CQ91 →
NDUFB4	NADH dehydrogenase [ubiquinone] 1 beta subcom	0.986	landscape →
P19173	—	0.986	P19173 →
Q02820	—	0.986	Q02820 →
P0CB71	—	0.986	P0CB71 →
P48305	—	0.986	P48305 →
Q54LT5	—	0.985	Q54LT5 →
P13271	—	0.985	P13271 →
A5E7J0	—	0.985	A5E7J0 →
Q5ACH7	—	0.984	Q5ACH7 →
P11950	—	0.984	P11950 →
Q9CQ69	—	0.984	Q9CQ69 →
Q6BL60	—	0.984	Q6BL60 →