SCHEMBL423627

SCHEMBL423627

CCc1c(N)cc(N)c(CC)c1C

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.37
ALOX15 P16050 2/20 0.37
CYP1A2 P05177 1/20 0.37
CASP7 P55210 1/20 0.37
HIF1A Q16665 1/20 0.37
HSD17B10 Q99714 1/20 0.37
PTK2 Q05397 1/20 0.37
NOS3 P29474 3/20 0.37
NOS2 P35228 3/20 0.37
CYP3A4 P08684 3/20 0.33
TSHR P16473 3/20 0.33
MAPK1 P28482 1/20 0.33
PIK3CA P42336 1/20 0.33
NOS1 P29475 1/20 0.32
MAPT P10636 2/20 0.31
POLB P06746 1/20 0.31
S100B P04271 1/20 0.31
KDM4E B2RXH2 1/20 0.31
TP53 P04637 1/20 0.31
THRB P10828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25162114 0.87 CYP3A4 (0.40) ALDH1A1ALOX15CYP1A2CASP7HIF1A
Benzidine SCHEMBL5609328 0.85 ALDH1A1 (0.44) ALDH1A1ALOX15HSD17B10NOS3NOS2
SCHEMBL28794153 0.84 ALDH1A1 (0.39) ALDH1A1ALOX15CYP1A2CASP7HIF1A
SCHEMBL28210094 0.80 ALDH1A1 (0.39) ALDH1A1ALOX15CYP1A2CASP7HIF1A
SCHEMBL10431866 0.79 ALDH1A1 (0.41) ALDH1A1ALOX15CYP1A2CASP7HIF1A
SCHEMBL12515037 0.78 ALDH1A1 (0.43) ALDH1A1ALOX15CYP1A2CASP7HIF1A
SCHEMBL28853125 0.77 SELL (0.36) ALDH1A1ALOX15HSD17B10MAPK1MAPT
SCHEMBL9847085 0.76 CYP3A4 (0.43) ALDH1A1ALOX15HSD17B10NOS3NOS2
SCHEMBL10594833 0.75 CYP3A4 (0.39) ALDH1A1ALOX15CYP1A2CASP7HIF1A
SCHEMBL17692465 0.74 PTK2 (0.39) ALDH1A1ALOX15CYP1A2CASP7HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1705 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11905381-B2 Polyimide microparticles XEROX CORPORATION (US) 2024-02-20 US claimed
US-20220363843-A1 POLYIMIDE MICROPARTICLES XEROX CORPORATION (US) 2022-11-17 US claimed
EP-4089136-A1 POLYIMIDE MICROPARTICLES Xerox Corporation (US) 2022-11-16 EP claimed
CN-115322398-A Polyimide fine particles 施乐公司 2022-11-11 CN claimed
WO-2021113491-A1 POLYIMIDE VARNISH FROM HIGH PURITY BISPHENOL A DIANHYDRIDE AND ARTICLES PREPARED THEREFROM SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2021-06-10 WO claimed
WO-2021113489-A1 POLYAMIC ACID VARNISH FROM HIGH PURITY BISPHENOL A DIANHYDRIDE AND ARTICLES PREPARED THEREFROM SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2021-06-10 WO claimed
EP-3233961-B1 HIGH-TEMPERATURE RESISTANT DUROMERS ON THE BASIS OF NAPHTHALENE-BASED EPOXY RESINS AND CYANATE ESTERS, AND IMPROVEMENT OF THE IMPACT STRENGTH AIRBUS DEFENCE & SPACE GMBH (DE) 2020-08-19 EP claimed
CN-102015833-B There is polyetherimide and the polyetherimide sulfone blends of automotive illumination applications SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2015-12-16 CN claimed
US-8592548-B2 Method to prepare bis(haloimides) SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2013-11-26 US claimed
US-8545988-B2 Polyetherimide and polyetherimide sulfone blends having automotive lighting applications SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2013-10-01 US claimed
US-20030216506-A1 Method of manufacture of polyester molding compositions and articles produced therefrom SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2003-11-20 US claimed
WO-2003080709-A1 PREPARATION OF POLYIMIDE POLYMERS GENERAL ELECTRIC COMPANY (US) 2003-10-02 WO claimed
US-20030181626-A1 Preparation of polyimide polymers SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2003-09-25 US claimed
US-20030125478-A1 HIGH PERFORMANCE THERMOPLASTIC COMPOSITIONS WITH IMPROVED MELT FLOW PROPERTIES SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2003-07-03 US claimed
WO-2003050165-A1 METHODS FOR THE PREPARATION OF POLY(ETHERIMIDES)S GENERAL ELECTRIC COMPANY (US) 2003-06-19 WO claimed
EP-1318174-A1 Method of manufacture of polyester molding compositions and articles produced therefrom GENERAL ELECTRIC COMPANY (US) 2003-06-11 EP claimed
WO-2003040213-A1 HIGH MOLECULAR WEIGHT POLY(IMIDE)S AND METHODS OF SYNTHESIS THEREOF GENERAL ELECTRIC COMPANY (US) 2003-05-15 WO claimed
US-6500904-B1 FROM THE COUPLING OF LOWER MOLECULAR WEIGHT FUNCTIONALIZED PRECURSOR POLYIMIDES GENERAL ELECTRIC COMPANY 2002-12-31 US claimed
US-6498224-B1 SOLUTION POLYMERIZATION OF A DIANHYDRIDE AND A DIAMINE WHICH ELIMINATES THE NITRATION STEP; HIGH HEAT ENGINEERING PLASTICS GENERAL ELECTRIC COMPANY 2002-12-24 US claimed
US-6350514-B1 POLYARYLENE ETHER AND POLYALKYLENEAROMATIC POLYMERS WITH AROMATIC AMINE FOR AUTOMOBILE INTERIORS WITH POLYURETHANES GENERAL ELECTRIC CO. 2002-02-26 US claimed