Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL423627 | 0.85 | ALDH1A1 (0.37) | ALDH1A1CYP3A4TDP1TP53HSD17B10 | |
| SCHEMBL25162114 | 0.74 | CYP3A4 (0.40) | ALDH1A1CYP3A4TDP1HSD17B10TSHR | |
| SCHEMBL5386508 | 0.73 | RPS6KA3 (0.38) | ALDH1A1CYP3A4TDP1TP53HSD17B10 | |
| Benzidine SCHEMBL6160242 | 0.72 | TDP1 (0.73) | ALDH1A1CYP3A4TDP1TP53HSD17B10 | |
| Benzidine SCHEMBL25422776 | 0.72 | TDP1 (0.73) | ALDH1A1CYP3A4TDP1TP53HSD17B10 | |
| Benzidine SCHEMBL501952 | 0.72 | ALDH1A1 (0.85) | ALDH1A1CYP3A4TDP1TP53HSD17B10 | |
| SCHEMBL28794153 | 0.72 | ALDH1A1 (0.39) | ALDH1A1CYP3A4TDP1HSD17B10TSHR | |
| Benzidine SCHEMBL29113244 | 0.71 | ALDH1A1 (0.42) | ALDH1A1CYP3A4TDP1TP53HSD17B10 | |
| SCHEMBL2574764 | 0.69 | ALDH1A1 (0.46) | ALDH1A1CYP3A4TDP1TP53HSD17B10 | |
| SCHEMBL9847085 | 0.69 | CYP3A4 (0.43) | ALDH1A1CYP3A4TDP1TP53HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7259201-B2 | Flame retardant thermoplastic films and methods of making the same | GENERAL ELECTRIC COMPANY (US) | 2007-08-21 | — | — | US | disclosed |