SCHEMBL4236308

SCHEMBL4236308

CO[Si](Cc1ccccc1)(OC)OCN

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LOXL2 Q9Y4K0 2/20 0.38
TAAR1 Q96RJ0 3/20 0.35
HTR2A P28223 2/20 0.35
CYP2A6 P11509 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
PRMT1 Q99873 1/20 0.35
IDO1 P14902 1/20 0.34
LTA4H P09960 1/20 0.34
TP53 P04637 1/20 0.33
AGXT P21549 1/20 0.33
MAOA P21397 2/20 0.32
CARM1 Q86X55 1/20 0.32
PRMT6 Q96LA8 1/20 0.32
PRMT8 Q9NR22 1/20 0.32
AOC3 Q16853 1/20 0.32
SLC6A2 P23975 1/20 0.32
SLC6A4 P31645 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methylamine SCHEMBL29141165 0.84 IDO1 (0.39) LOXL2TAAR1HTR2ACYP2A6SMN1; SMN2
SCHEMBL104953 0.83 TP53 (0.42) LOXL2TAAR1IDO1LTA4HTP53
SCHEMBL28534659 0.82 LTA4H (0.35) TAAR1IDO1LTA4HTP53SIGMAR1
SCHEMBL19816647 0.82 TP53 (0.39) TAAR1SMN1; SMN2CYP1A2CYP3A4CYP2D6
SCHEMBL2488885 0.81 HTR2A (0.42) LOXL2TAAR1HTR2ACYP2A6SMN1; SMN2
SCHEMBL32671379 0.81 LTA4H (0.34) TAAR1IDO1LTA4HTP53
SCHEMBL32671323 0.81 ALDH1A1 (0.37) TAAR1IDO1LTA4HTP53
SCHEMBL32671232 0.81 LTA4H (0.34) TAAR1LTA4HTP53SIGMAR1
SCHEMBL28045036 0.81 TSHR (0.38) TAAR1IDO1LTA4HTP53
SCHEMBL1972981 0.81 LTA4H (0.34) TAAR1IDO1LTA4HTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009153274-A1 EPOXY-BASED ADHESIVE OR SEALANT COMPRISING INORGANIC NANOPARTICLES WITH ACRYLIC ACID ESTER-CONTAINING CASING HENKEL AG & CO. KGAA (DE) 2009-12-23 WO disclosed