Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 11/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 11/20 | 0.39 |
| ▸ | HTR5A | P47898 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4227446 | 0.78 | HTT (0.37) | KDM4EALDH1A1HTTKMT2A | |
| Trifluoroacetic Acid SCHEMBL4227076 | 0.75 | GRM7 (0.48) | KDM4EALDH1A1POLBKMT2A | |
| SCHEMBL4237168 | 0.71 | MTNR1A (0.34) | MTNR1AMTNR1B | |
| Trifluoroacetic Acid SCHEMBL4226991 | 0.69 | KDM1A (0.56) | — | |
| Trifluoroacetic Acid SCHEMBL4226583 | 0.69 | MTNR1A (0.53) | MTNR1AMTNR1B | |
| SCHEMBL6635131 | 0.67 | MTNR1A (0.49) | MTNR1AMTNR1BKDM4EOPRM1OPRL1 | |
| SCHEMBL27790237 | 0.65 | MTNR1A (0.49) | MTNR1AMTNR1BKDM4EALDH1A1OPRM1 | |
| SCHEMBL23300515 | 0.64 | MTNR1A (0.41) | MTNR1AMTNR1BOPRM1OPRL1 | |
| Hydrochloric Acid SCHEMBL4235489 | 0.64 | GRIN2B (0.52) | MTNR1AMTNR1BKDM4EPOLBKMT2A | |
| Trifluoroacetic Acid SCHEMBL4225508 | 0.64 | HDAC3 (0.48) | HTR5AHTTLMNAOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2096104-A1 | Organic diamines as mGluR7 modulators | Novartis AG (CH) | 2009-09-02 | — | — | EP | disclosed |
| US-20080242698-A1 | Organic Compounds | NOVARTIS AG (CH) | 2008-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080242698-A1 | Organic Compounds | AOC1, OTC, ODC1 | MTNR1A 2710/4885MTNR1B 2160/4885HTR5A 1348/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.