SCHEMBL423720

SCHEMBL423720

CCCSSc1ccccn1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EHMT2 Q96KQ7 1/20 0.59
EHMT1 Q9H9B1 1/20 0.59
APOBEC3G Q9HC16 1/20 0.59
ALDH1A1 P00352 4/20 0.42
LMNA P02545 1/20 0.41
KMT2A Q03164 2/20 0.39
MAPT P10636 1/20 0.39
RAB9A P51151 4/20 0.39
NPC1 O15118 3/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
TDP1 Q9NUW8 1/20 0.39
SMN1; SMN2 Q16637 3/20 0.37
HPGD P15428 2/20 0.37
MEN1 O00255 1/20 0.37
TSHR P16473 1/20 0.37
KDM4E B2RXH2 1/20 0.37
ALOX15 P16050 1/20 0.37
HSD17B10 Q99714 1/20 0.37
KDM1A O60341 2/20 0.37
KCNA5 P22460 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30195130 1.00 EHMT2 (0.59) EHMT2EHMT1APOBEC3GALDH1A1LMNA
SCHEMBL12107793 0.89 EHMT2 (0.55) EHMT2EHMT1APOBEC3GALDH1A1LMNA
SCHEMBL30195173 0.89 EHMT2 (0.55) EHMT2EHMT1APOBEC3GALDH1A1LMNA
SCHEMBL11833495 0.88 EHMT2 (0.70) EHMT2EHMT1APOBEC3GALDH1A1LMNA
SCHEMBL463670 0.87 EHMT2 (0.53) EHMT2EHMT1APOBEC3GALDH1A1LMNA
SCHEMBL23963850 0.86 EHMT2 (0.52) EHMT2EHMT1APOBEC3GALDH1A1LMNA
SCHEMBL3487114 0.86 EHMT2 (0.52) EHMT2EHMT1APOBEC3GALDH1A1LMNA
SCHEMBL10077568 0.86 EHMT2 (0.52) EHMT2EHMT1APOBEC3GALDH1A1LMNA
SCHEMBL31291173 0.86 EHMT2 (0.52) EHMT2EHMT1APOBEC3GALDH1A1LMNA
SCHEMBL19104359 0.86 EHMT2 (0.52) EHMT2EHMT1APOBEC3GALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12492263-B2 Anti-HER2 antibodies and immunoconjugates GENENTECH, INC. (US) 2025-12-09 US disclosed
US-20230323434-A1 GENERATING CAPTURE PROBES FOR SPATIAL ANALYSIS 10X GENOMICS, INC. 2023-10-12 US disclosed
WO-2023180953-A1 INHIBITORS OF HUMAN SLC7A3 FOR THE TREATMENT OF ENDOMETRIOSIS OR UTERINE FIBROIDS GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.3) LIMITED (GB) 2023-09-28 WO disclosed
US-20230041134-A1 Anti-HER2 Antibodies and Immunoconjugates GENENTECH, INC. (US) 2023-02-09 US disclosed
WO-2022106703-A1 PROTECTED DISACCHARIDES, THEIR PROCESS OF PREPARATION AND THEIR USE IN THE SYNTHESIS OF ZWITTERIONIC OLIGOSACCHARIDES, AND CONJUGATES THEREOF INSTITUT PASTEUR (FR) 2022-05-27 WO disclosed
CN-113039191-A Nucleotide analogs 奇异基因组学系统公司 2021-06-25 CN disclosed
EP-3448864-B1 SILSESQUIOXANES AS TRANSPORT COMPOUNDS UNIV DARMSTADT TECH (DE) 2021-06-23 EP disclosed
EP-3782654-A1 ANTI-HER2 ANTIBODIES AND IMMUNOCONJUGATES Genentech, Inc. (US) 2021-02-24 EP disclosed
US-20200046845-A1 CYCLODEXTRIN-BASED POLYMERS FOR THERAPEUTIC DELIVERY CERULEAN PHARMA INC. 2020-02-13 US disclosed
EP-3569251-A1 CONJUGATES CONTAINING HYDROPHILIC SPACER LINKERS Endocyte, Inc. (US) 2019-11-20 EP disclosed
US-20070269806-A1 Polynucleotide Arrays ILLUMINA CAMBRIDGE LIMITED (GB) 2007-11-22 US disclosed
WO-2007127473-A2 POLY (ETHYLENE GLYCOL) CONTAINING CHEMICALLY DISPARATE ENDGROUPS INTEZYNE TECHNOLOGIES, INC. (US) 2007-11-08 WO disclosed
US-5413913-A Autoagglutination prevention; medical diagnosis AGEN BIOMEDICAL, LTD. (AU) 1995-05-09 US disclosed
EP-0308242-B1 Agglutination assay AGEN LTD (AU) 1995-01-04 EP disclosed
US-5086002-A Detecting antigen, antibody AGEN BIOMEDICAL, LTD. (AU) 1992-02-04 US disclosed
EP-0308242-A2 Agglutination assay AGEN LIMITED (AU) 1989-03-22 EP disclosed
US-4237290-A ODORANTS, FLAVORINGS; REACTION OF A SULFONIUM SALT AND A MERCAPTAN GIVAUDAN CORPORATION (US) 1980-12-02 US disclosed
US-4188488-A ALKYLIMIDAZOLYL SUBSTITUENTS GIVAUDAN CORPORATION (US) 1980-02-12 US disclosed
US-4170594-A Oxazolyl-alkyl-disulphides as flavorants GIVAUDAN CORPORATION (US) 1979-10-09 US disclosed
US-4130562-A Odorant or flavoring thiazolyl disulphides GIVAUDAN CORPORATION (US) 1978-12-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12492263-B2 Anti-HER2 antibodies and immunoconjugates ERBB2, EGFR, ERBB3 EHMT2 1031/4885EHMT1 2274/4885APOBEC3G 1092/4885
US-20070269806-A1 Polynucleotide Arrays PCNA, NCL, POLN EHMT2 2094/4885EHMT1 2492/4885APOBEC3G 271/4885
US-20230041134-A1 Anti-HER2 Antibodies and Immunoconjugates ERBB2, EGFR, ERBB3 EHMT2 1031/4885EHMT1 2274/4885APOBEC3G 1092/4885
US-20200046845-A1 CYCLODEXTRIN-BASED POLYMERS FOR THERAPEUTIC DELIVERY CDR2, DDOST, GALC EHMT2 3727/4885EHMT1 3809/4885APOBEC3G 3115/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.