Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR5 | P35346 | 11/20 | 0.49 |
| ▸ | HRH1 | P35367 | 2/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.45 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4232088 | 0.89 | SSTR5 (0.44) | SSTR5HRH1HTR2BSSTR1KCNH2 | |
| SCHEMBL4234809 | 0.89 | SSTR5 (0.44) | SSTR5HRH1HTR2BSSTR1KCNH2 | |
| SCHEMBL4232885 | 0.85 | SSTR5 (0.46) | SSTR5HRH1SSTR1KCNH2ALDH1A1 | |
| SCHEMBL4232220 | 0.85 | SSTR5 (0.46) | SSTR5HRH1KCNH2ALDH1A1SMN1; SMN2 | |
| SCHEMBL4236623 | 0.85 | SSTR5 (0.41) | SSTR5KCNH2UTS2RALDH1A1SMN1; SMN2 | |
| SCHEMBL4957097 | 0.85 | SSTR5 (0.52) | SSTR5HRH1HTR2BSSTR1KCNH2 | |
| SCHEMBL4958186 | 0.85 | SSTR5 (0.51) | SSTR5HRH1HTR2BSSTR1KCNH2 | |
| SCHEMBL4233908 | 0.82 | SSTR5 (0.44) | SSTR5HRH1HTR2BKCNH2ALDH1A1 | |
| SCHEMBL4227033 | 0.82 | SSTR5 (0.45) | SSTR5HRH1HTR2BSSTR1KCNH2 | |
| SCHEMBL4237976 | 0.82 | SLC2A1 (0.46) | SSTR5HRH1HTR2BSSTR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2001867-B1 | PYRIMIDINE, QUINAZOLINE, PTERIDINE AND TRIAZINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2009-07-01 | — | — | EP | disclosed |