Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.46 |
| ▸ | SSTR5 | P35346 | 11/20 | 0.43 |
| ▸ | HRH1 | P35367 | 4/20 | 0.43 |
| ▸ | HTR2B | P41595 | 2/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.40 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.39 |
| ▸ | KDM1A | O60341 | 3/20 | 0.38 |
| ▸ | RCOR1 | Q9UKL0 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4381976 | 0.91 | SLC2A1 (0.44) | SLC2A1SSTR5HRH1HTR2BNSD2 | |
| SCHEMBL4232008 | 0.88 | SLC2A1 (0.44) | SLC2A1SSTR5NSD2EHMT2KDM1A | |
| SCHEMBL4237355 | 0.82 | SSTR5 (0.49) | SSTR5HRH1HTR2BSSTR1MEN1 | |
| SCHEMBL4237974 | 0.82 | SLC2A1 (0.43) | SLC2A1SSTR5HRH1HTR2BNSD2 | |
| SCHEMBL3785396 | 0.80 | SSTR5 (0.58) | SSTR5HRH1HTR2BNSD2EHMT2 | |
| SCHEMBL4237980 | 0.79 | SLC2A1 (0.42) | SLC2A1SSTR5HRH1HTR2BNSD2 | |
| Hydrochloric Acid SCHEMBL4221593 | 0.76 | SSTR5 (0.45) | SLC2A1SSTR5HRH1HTR2BSSTR1 | |
| SCHEMBL4227033 | 0.75 | SSTR5 (0.45) | SSTR5HRH1HTR2BSSTR1 | |
| SCHEMBL4234809 | 0.75 | SSTR5 (0.44) | SSTR5HRH1HTR2BSSTR1 | |
| SCHEMBL4231381 | 0.74 | EHMT2 (0.52) | SSTR5HRH1HTR2BNSD2EHMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2001867-B1 | PYRIMIDINE, QUINAZOLINE, PTERIDINE AND TRIAZINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2009-07-01 | — | — | EP | disclosed |