SCHEMBL4237429

SCHEMBL4237429

CC(C)N1CCCCC1Cc1ccc(C(=O)O)cc1

nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 1/20 0.44
KMT2A Q03164 3/20 0.43
EPHX1 P07099 1/20 0.40
CHRM3 P20309 1/20 0.40
LTA4H P09960 1/20 0.40
MEN1 O00255 2/20 0.40
PTGER4 P35408 2/20 0.39
PTGER2 P43116 1/20 0.39
ALDH1A1 P00352 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2603288 0.83 SLC18A2 (0.49)
SCHEMBL11486266 0.79 CCR3 (0.42) ALDH1A1
SCHEMBL11479223 0.79 KDM4E (0.44) HRH3ALDH1A1
SCHEMBL2603270 0.78 SLC18A2 (0.50) CHRM3
SCHEMBL13995045 0.78 SLC18A2 (0.50) CHRM3
SCHEMBL26729863 0.76 CHRM3 (0.48) CHRM3LTA4HPTGER4PTGER2ALDH1A1
SCHEMBL11372466 0.76 CHI3L1 (0.43) HRH3ALDH1A1
SCHEMBL4331452 0.74 SLC18A2 (0.46)
SCHEMBL3812261 0.74 DAGLA (0.46) KMT2ALTA4H
SCHEMBL14417578 0.73 HRH3 (0.49) HRH3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090233910-A1 Npy antagonists, preparation and uses CEREP (FR) 2009-09-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090233910-A1 Npy antagonists, preparation and uses NPY1R, NPY5R, NPY2R HRH3 210/4885KMT2A 3436/4885EPHX1 1849/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.